This study was a multi-reader, multi-institutional, IRB-approved retrospective analysis of 93 HGSOC patients with abdominal and pelvic CT scans prior to primary debulking that were available through The Cancer Imaging Archive (TCIA). Eight radiologists from The Cancer Genome Atlas-Ovarian Cancer (TCGA-OV) Imaging Research Group developed and subsequently independently recorded the following CT features in each patient: primary ovarian mass(es) characteristics (if present), presence and distribution of peritoneal tumor spread, lymphadenopathy, and distant metastases. Inter-observer agreement for the CT features was assessed, as were associations of these features with time-to-disease progression (TTP) and CLOVAR subtypes and abilities of combinations of these features to predict TTP and CLOVAR subtypes. Results of analyzing this data are published in a manuscript titled Radiogenomics of High-Grade Serous Ovarian Cancer: Multi- Reader Multi-Institutional Study from The Cancer Genome Atlas-Ovarian Cancer (TCGA-OV) Imaging Research Group.
Click the Download button to save a ".tcia" manifest file to your computer, which you must open with the NBIA Data Retriever
|Data Type||Download all or Query/Filter|
Full Radiologist Assessments of Image Features (CSV)
Consensus Radiologist Assessments of Image Features (CSV)
|Clinical data (CSV)|
|Genomic sub-type data (CSV)|
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Citations & Data Usage Policy
These collections are freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. Questions may be directed to firstname.lastname@example.org. Please be sure to acknowledge both this data set and TCIA in publications by including the following citations in your work:
Vargas, Alberto; Huang, Erich; Lakhman, Yulia; Ippolito, Joe; Bhosale, Priya; Mellnick, Vincent; Shinagare, Atul; Anello, Maria; Kirby, Justin; Fevrier-Sullivan, Brenda; Freymann, John; Jaffe, Carl; Sala, Evis,. (2016). Imaging Features, and Correlations with Genomic and Clinical Data from the TCGA Ovarian Radiology Research Group. The Cancer Imaging Archive. http://doi.org/10.7937/K9/TCIA.2016.PSJOXM47
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)