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Summary

Excerpt

The Cancer Genome Atlas (TCGA) Prostate Phenotype Research Group is part of the

CIP

Cancer Imaging Project TCGA Radiology

Initiative

Initiative focused on analyzing images from the TCGA- Prostate Adenocarcinoma (PRAD) collections. Images which correlate to the

Prostate Adenocarcinoma

PRAD tissue data in

the TCGA

TCGA’s Data Portal are

continuing to be

being gathered for submission to The Cancer Imaging Archive (TCIA).

According to the TCGA page on Prostate AdenocarcinomaPRAD, researchers hope to make the following types of discoveries with this data:

  • Analyze correlation between Gleason score and other tumor characteristics to better define aggressiveness.
  • Examine samples from majority populations and compare to underrepresented populations, such as African Americans who have the highest incidence rate of prostate cancer.
  • Integrate the genomic information with the proteomic data.

Research and Publications

Per TCGA and TCIA Guidelines, formal permission requests are still required to submit publications using TCGA-PRAD data.  Please see the following links for more information about the freedom-to-publish criteria for these data sets:

Data Source

Status

TCGA Data Portal Publication Guidelines

Projects have not reached 100 cases; Please please check with TCGA prior to any publication.

TCIA Data Usage Policies and Restrictions

Projects have not reached 100 imaging cases; Please please check with cancerimagingarchive@mail.nih.gov prior to any publication.

Please contact us at cancerimagingarchive@mail.nih.gov if you have any questions about these policies.

...

Imaging Source Site (ISS) Groups will be populated and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these ISS groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this type per TCGA Publication Guidelines. This opportunity will generate increased participation in the building of these multi-institutional data sets that as they become an open community resource.  Current  Current TCGA-PRAD source sites include:

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Please contact Dr. Matthew Heller (hellermt@upmc.edu) if you have scientific questions you would like to direct to the for TCGA-PRAD ISS or are interested in collaborating with their group.

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The following links contain publications from the main TCGA project , as well as their posted publication guidelines.: