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This dataset contains image annotations derived from the NCI Clinical Trial "Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms Tumor (AREN0533)”. The key objective of this project is to generate a large and highly curated imaging dataset of pediatric Wilms tumor patients with annotations suitable for cancer researchers and AI developers. Annotation ProtocolFor each patient, every DICOM Study and DICOM Series was reviewed to identify and annotate the clinically relevant time points and sequences. In a typical patient the following time points will be annotated:
In a typical patient the following annotation rules were followed:
At each timepoint volumetric segmentations, seed points and negative finding assessments (DICOM RTSTRUCT) were created. SNOMED-CT “Anatomic Region Sequence” and “Segmented Property Category Code Sequence” and codes were inserted for all segmented structures. Imaging time point codes were inserted to help identify each annotation in the context of the clinical trial assessment protocol. “Clinical Trial Time Point ID” was used to encode time point type using one of the following strings as applicable: “pre-dose” or “post-chemotherapy”. The Content Item in “Acquisition Context Sequence” was added containing "Time Point Type" using Concept Code Sequence (0040,A168) selected from:
Important supplementary information and sample code
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