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All the images are diagnostic contrast enhanced CT scans. The images were retrospectively acquired, to ensure sufficient patient follow-up. Slice thickness is variable : between 3 and 6 mm. All images were done at diagnosis and prior to surgery. The objective of the study was to extract prognostic image features that will describe lung adenocarcinomas and will associate with overall survival.  

Two CT features were developed to quantitatively describe lung adenocarcinomas by scoring tumor shape complexity and intratumor density variation using routinely obtained diagnostic CT scans. The features systematically scored tumors and identified imaging phenotypes which exhibited survival differences. The features were extracted from routinely obtained CT images and were reproducible and stable despite the inherent clinical image acquisition variability. Our results suggest that quantitative imaging features can be used as an additional diagnostic tool in management of lung adenocarcinomas. More information is available in the related publication (see Citation tab below).


We would like to acknowledge the individual and institution that have provided data for this collection:

  • Moffitt Cancer Center (Tampa Florida) - Special thanks to Olya Stringfield, PhD  from the Department of Cancer Imaging and Metabolism .
Localtab Group

titleData Access

Data Access

Click the  Download button to save a ".tcia" manifest file to your computer, which you must open with the NBIA Data Retriever . Click the Search button to open our Data Portal, where you can browse the data collection and/or download a subset of its contents.

Data TypeDownload all or Query/Filter
Images (DICOM, 2.5GB)


DICOM Metadata Digest (CSV)
Representative Tumor Slices (XLS)
Clinical Data (DOC)

Click the Versions tab for more info about data releases.

Third Party Analyses of this Dataset

TCIA encourages the community to publish your analyses of our datasets. Below is a list of such third party analyses published using this Collection:

titleDetailed Description

Detailed Description

Collection Statistics

Updated 12/30/2014



Number of Participants


Number of Studies


Number of Series


Number of Images


Images Size (GB)2.5

TCIA DICOM Subject ID, SOP Instance UID, Instance Number, and Image Position (Patient) X-Y-Z  are noted in Representative-Tumor-Slices.xlsx

The accompanying data  are survival data (status: dead or alive, survival time in months) and pathological stage (TNM).  

titleCitations & Data Usage Policy

Citations & Data Usage Policy 

This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to

Please be sure to include the following citations in your work if you use this data set:

Public collection license
titleData Citation

Grove O, Berglund AE, Schabath MB, Aerts HJWL, Dekker A, Wang H, Velazquez ER, Lambin P, Gu Y, Balagurunathan Y, Eikman E, Gatenby RA, Eschrich S, Gillies RJ.  (2015). Data from: Quantitative computed tomographic descriptors associate tumor shape complexity and intratumor heterogeneity with prognosis in lung adenocarcinoma. The Cancer Imaging Archive.

titlePublication Citation

Grove O, Berglund AE, Schabath MB, Aerts HJWL, Dekker A, Wang H, Velazquez ER, Lambin P, Gu Y, Balagurunathan Y, Eikman E, Gatenby RA, Eschrich S, Gillies RJ. (2015). Quantitative Computed Tomographic Descriptors Associate Tumor Shape Complexity and Intratumor Heterogeneity with Prognosis in Lung Adenocarcinoma. (A. Muñoz-Barrutia, Ed.)PLOS ONE. Public Library of Science (PLoS).

titleTCIA Citation

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057.DOI:

Other Publications Using This Data

TCIA maintains a list of publications that leverage our data.  If you have a publication you'd like to add, please contact the TCIA Helpdesk.


Version 1 (Current): Updated 2014/12/30

Data TypeDownload all or Query/Filter
Images (DICOM, 2.5GB)


(Requires the NBIA Data Retriever .)

DICOM Metadata Digest (CSV)
Representative Tumor Slices (XLS)
Clinical Data (DOC)