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Data Access

Click the Download button to save a ".tcia" manifest file to your computer, which you must open with the NBIA Data Retriever. Click the Search button to open our Data Portal, where you can browse the data collection and/or download a subset of its contents.

Data Type	Download all or Query/Filter
Images (DICOM, 73.5GB)	Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/1966258/TCIA_TCGA-GBM_09-16-2015.tcia?api=v2 Tcia button generator label Search url https://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=TCGA-GBM (Download requires the NBIA Data Retriever)Image Removed  Image Removed
Tissue Slide Images (web)	Tcia button generator ext true label Search url https://portal.gdc.cancer.gov/legacy-archive/search/f?filters=%7B%22op%22:%22and%22,%22content%22:%5B%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22files.data_format%22,%22value%22:%5B%22SVS%22%5D%7D%7D,%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22cases.project.program.name%22,%22value%22:%5B%22TCGA%22%5D%7D%7D,%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22cases.project.project_id%22,%22value%22:%5B%22TCGA-GBM%22%5D%7D%7D%5D%7D Image Removed
Clinical Data (TXT)	Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/1966258/gdc_download_clinical_gbm.tar.gz?api=v2
Biomedical Data (TXT)	Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/1966258/gdc_download_biomedical_gbm.tar.gz?api=v2 Image Removed
Genomics (web)	Tcia button generator ext true label Search url https://portal.gdc.cancer.gov/projects/TCGA-GBM Image Removed

Click the Versions tab for more info about data releases.

Third Party Analyses of this Dataset

TCIA encourages the community to publish your analyses of our datasets. Below is a list of such third party analyses published using this Collection:

• MRQy quality measures for TCIA MRI datasets (MRQy-Quality-Measures)
• Segmentation Labels and Radiomic Features for the Pre-operative Scans of the TCGA-GBM collection (BraTS-TCGA-GBM)
• DICOM-SEG Conversions for TCGA-LGG and TCGA-GBM Segmentation Datasets (DICOM-Glioma-SEG)
• MR Imaging Predictors of Molecular Profile and Survival: Multi-institutional Study of the TCGA Glioblastoma Data Set (TCGA-GBM-Radiogenomics)
• Outcome Prediction in Patients with Glioblastoma by Using Imaging, Clinical, and Genomic Biomarkers: Focus on the Nonenhancing Component of the Tumor (GBM-MR-NER-Outcomes)
• Glioblastoma multiforme: exploratory radiogenomic analysis by using quantitative image features (TCGA-GBM-QI-Radiogenomics)
• Image Data Used in the Simulations of "The Role of Image Compression Standards in Medical Imaging: Current Status and Future Trends"
• Glioblastoma: Imaging Genomic Mapping Reveals Sex-specific Oncogenic Associations of Cell Death
• Spatial Habitat Features derived from Multiparametric Magnetic Resonance Imaging data from Glioblastoma Multiforme cases

Detailed Description

GDC Data Portal - Clinical and Genomic Data

The GDC Data Portal has extensive clinical and genomic data, which can be matched to the patient identifiers of the images here in TCIA. Below is a snapshot of clinical data extracted on 1/5/2016:

• TCGA-GBM Clinical Data.zip  ( NOTE: this is just a representative sample of what's available. Visit the GDC Data Portal to obtain the latest/complete data set)

Explanations of the clinical data can be found on the Biospecimen Core Resource Clinical Data Forms linked below:

• GBM Case Quality Control Form
• GBM Enrollment Form
• GBM Follow-Up Form

A Note about TCIA and TCGA Subject Identifiers and Dates

Subject Identifiers: a subject with radiology images stored in TCIA is identified with a Patient ID that is identical to the Patient ID of the same subject with demographic, clinical, pathological, and/or genomic data stored in TCGA. For each TCGA case, the baseline TCGA imaging studies found on TCIA are pre-surgical. 

Dates: TCIA and TCGA handle dates differently, and there are no immediate plans to reconcile:

• TCIA Dates: dates (be they birth dates, imaging study dates, etc.) in the Digital Imaging and Communications in Medicine (DICOM) headers of TCIA radiology images have been offset by a random number of days. The offset is a number of days between 3 and 10 years prior to the real date that is consistent for each TCIA image-submitting site and collection, but that varies among sites and among collections from the same site. Thus, the number of days between a subject’s longitudinal imaging studies are accurately preserved when more than one study has been archived while still meeting HIPAA requirements.
• TCGA Dates: the patient demographic and clinical event dates are all the number of days from the index date, which is the actual date of pathologic diagnosis. So all the dates in the data are relative negative or positive integers, except for the “days_to_pathologic_diagnosis” value, which is 0 – the index date. The years of birth and diagnosis are maintained in the distributed clinical data file. The NCI retains a copy of the data with complete dates, but those data are not made available.With regard to other TCGA dates, if a date comes from a HIPAA “covered entity’s” medical record, it is turned into the relative day count from the index date. Dates like the date TCGA received the specimen or when the TCGA case report form was filled out are not such covered dates, and they will appear as real dates (month, day, and year).

Citations & Data Usage Policy 

This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License.  See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.

Please be sure to include the following attribution and citations in your work if you use this data set:

 Other Publications Using This Data

See the TCGA-GBM section on our TCIA Publications page for other work leveraging this collectionTCIA collections. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.

Version

4 (Current): Updated 2020/05/29

Updated clinical data link with latest spreadsheets from GDC. Added new biomedical spreadsheets from GDC.

Version 3: Updated 2015/09/16

Data Type	Download all or Query/Filter
Images (DICOM, 8873.1GB5GB)	(Download requires the NBIA Data Retriever .)
Clinical Data (TXT)
Genomics (web)

 1 new subject added.

Version 2: Updated 2016/01/05

Data Type	Download all or Query/Filter
Images (DICOM, 8872.1GB8GB)	(Download requires the NBIA Data Retriever .)
Clinical Data (TXT)
Genomics (web)

Extracted latest release of clinical data (TXT) from the GDC Data Portal.

Version 1: Updated 2014/12/30

Data Type	Download all or Query/Filter
Images (DICOM, 8872.1GB8GB)
Clinical Data (TXT)
Genomics (web)

On 03-01-2013 available s ubjects in TCIA were reduced from 279 to 240 because some cases were subsequently excluded from the GDC Data Portal.