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Data collection and analysis was provided by Anant Madabhushi, PhD, Case Western Reserve University and Michael D. Feldman, MD, PhD, Hospital at the University of Pennsylvania.  This work was supported by NIH R01CA136535.

References

  1. Singanamalli, A. , Rusu, M. , Sparks, R, Rusu, M. E., Shih, N. N., Ziober, A. , Wang, L. , Tomaszewski, J. , Rosen, M. , Feldman, M, . and Madabhushi, A. (2016), “Identifying Identifying in vivo DCE MRI markers associated with Microvessel Architecture and Gleason Grades of Prostate Cancer—Preliminary Findings”, Journal of Magnetic Resonance Imaging, microvessel architecture and gleason grades of prostate cancer. J. Magn. Reson. Imaging, 43: 149-158. doi:10.1002/jmri.24975. [Epub ahead of print]  (PMID:26110513).
  2. Toth, R, Feldman, M, Yu, D, Tomaszewski, J, Madabhushi, A, “Histostitcher™. “Histostitcher™: An Informatics Software Platform for Reconstructing Whole-Mount Prostate Histology using the Extensible Imaging Platform (XIP™) Framework,” Journal of Pathology Informatics, vol. 5, pg. 8, 2014 (PMID: 24843820, PMCID: PMC4023035).
  3. Xiao, G, Bloch, N, Chappelow, J, Genega, E, Rofsky, N, Lenkinsky, R, Tomaszewski, J, Feldman, M, Rosen, M, Madabhushi, A, “Determining . “Determining Histology-MRI Slice Correspondences for Defining MRI-based Disease Signatures of Prostate Cancer,” Special Issue of Computerized Medical Imaging and Graphics on Whole Slide Microscopic Image Processing, vol. 35[7-8], pp. 568-78, 2011 (PMID: 21255974).
  4. Chappelow, J, Bloch, N., Rofsky, N, Genega, E, Lenkinski, R, DeWolf, W, Madabhushi, A,   “Elastic .  “Elastic Registration of Multimodal Prostate MRI and Histology via Multi-Attribute Combined Mutual Information,” Medical Physics, vol. 38[4], pp. 2005-2018, 2011 (PMID: 21626933).

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Localtab Group



Localtab
activetrue
titleData Access

Data

Access (Radiology)

Access 

Click the  Download button to save a ".tcia" manifest file to your computer, which you must open with the NBIA Data Retriever . Click the Search button to open our Data Portal, where you can browse the data collection and/or download a subset of its contents.


Data TypeDownload all or Query/Filter
Images (DICOM, 4.4 GB)

Annotated Whole Slide Pathology Images

Image Removed

& Annotations (Tiff, XML 76.8 GB)

Fused Rad-Path Matlab Files
Image Removed

 


Please note that Box has a 15GB download limit, so you will need to download images in batches.

Click the Versions tab for more info about data releases.




Localtab
titleDetailed Description

Detailed Description


Collection Statistics

Radiology Image Statistics

 
Pathology Image Statistics

Modalities

MRI

,

Pathology, Matlab

Number of

Patients

Participants

28

16

Number of Studies

29

N/A

Number of Series

325N/A

Number of Images

32,508

32508
114
Image Size (GB)4.476.8


Supporting Documentation

The data set is fully described in the following publications:

 

  1. Singanamalli, A. , Rusu, M. , Sparks, R, Rusu, M. E., Shih, N. N., Ziober, A. , Wang, L. , Tomaszewski, J. , Rosen, M. , Feldman, M, . and Madabhushi, A. (2016), “Identifying Identifying in vivo DCE MRI markers associated with Microvessel Architecture and Gleason Grades of Prostate Cancer—Preliminary Findings”, Journal of Magnetic Resonance Imaging, microvessel architecture and gleason grades of prostate cancer. J. Magn. Reson. Imaging, 43: 149-158. doi:10.1002/jmri.24975. [Epub ahead of print]  (PMID:26110513).
  2. Toth, R, Feldman, M, Yu, D, Tomaszewski, J, Madabhushi, A, “Histostitcher™Histostitcher™: An Informatics Software Platform for Reconstructing Whole-Mount Prostate Histology using the Extensible Imaging Platform (XIP™) Framework,” Journal of Pathology Informatics, vol. 5, pg. 8, 2014 (PMID: 24843820, PMCID: PMC4023035).
  3. Xiao, G, Bloch, N, Chappelow, J, Genega, E, Rofsky, N, Lenkinsky, R, Tomaszewski, J, Feldman, M, Rosen, M, Madabhushi, A, “Determining Determining Histology-MRI Slice Correspondences for Defining MRI-based Disease Signatures of Prostate Cancer,” Special Issue of Computerized Medical Imaging and Graphics on Whole Slide Microscopic Image Processing, vol. 35[7-8], pp. 568-78, 2011 (PMID: 21255974).
  4. Chappelow, J, Bloch, N., Rofsky, N, Genega, E, Lenkinski, R, DeWolf, W, Madabhushi, A,   “Elastic Elastic Registration of Multimodal Prostate MRI and Histology via Multi-Attribute Combined Mutual Information,” Medical Physics, vol. 38[4], pp. 2005-2018, 2011 (PMID: 21626933).
Pathology and Matlab Data

Reconstructed, annotated whole slide pathology as well as fused Rad-Path matlab objects are also available at https://pathology.cancerimagingarchive.net/pathdata/.





Localtab
titleCitations & Data Usage Policy

Citations & Data Usage Policy 

 This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License.  See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.

Please be sure to include the following citations in your work if you use this data set:

Public collection license

Info
titleData Citation

Madabhushi, A., & Feldman, M. (2016). Fused Radiology-Pathology Prostate Dataset . The Cancer Imaging Archive. http://doi.org/doi; 10.7937/K9/TCIA.2016.TLPMR1AM




Info
titlePublication Citation
  1. Singanamalli, A. , Rusu, M. , Sparks, R. E., Shih, N. N., Ziober, A. , Wang, L. , Tomaszewski, J. , Rosen, M. , Feldman, M. and Madabhushi, A. (2016), Identifying in vivo DCE MRI markers associated with microvessel architecture and gleason grades of prostate cancer. J. Magn. Reson. Imaging, 43: 149-158. doi: 10.1002/jmri.24975 (PMID:26110513).
  2. Toth, R, Feldman, M, Yu, D, Tomaszewski, J, Madabhushi, A, “Histostitcher™: An Informatics Software Platform for Reconstructing Whole-Mount Prostate Histology using the Extensible Imaging Platform (XIP™) Framework,” Journal of Pathology Informatics, vol. 5, pg. 8, 2014 (PMID: 24843820, PMCID: PMC4023035).
  3. Xiao, G, Bloch, N, Chappelow, J, Genega, E, Rofsky, N, Lenkinsky, R, Tomaszewski, J, Feldman, M, Rosen, M, Madabhushi, A, “Determining Histology-MRI Slice Correspondences for Defining MRI-based Disease Signatures of Prostate Cancer,” Special Issue of Computerized Medical Imaging and Graphics on Whole Slide Microscopic Image Processing, vol. 35[7-8], pp. 568-78, 2011 (PMID: 21255974). https://doi.org/10.1016/j.compmedimag.2010.12.003
  4. Chappelow, J, Bloch, N., Rofsky, N, Genega, E, Lenkinski, R, DeWolf, W, Madabhushi, A,   “Elastic Registration of Multimodal Prostate MRI and Histology via Multi-Attribute Combined Mutual Information,” Medical Physics, vol. 38[4], pp. 2005-2018, 2011 (PMID: 21626933).




Info
titleTCIA Citation

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)


Other Publications Using This Data

TCIA maintains a list of publications that leverage our data. At this time we are not aware of any publications based on this data. If you have a publication you'd like to add, please contact the TCIA Helpdesk. 





Localtab
titleVersions

Version 1 (Current) Updated 11-30-2016


Data TypeDownload all or Query/Filter
Images (DICOM, 4.4 GB)
Annotated Whole Slide Pathology Images
Image Removed
& Annotations (Tiff, XML 76.8 GB)

Image Added    Image Added                   

Fused Rad-Path MATLAB Files