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Summary

Excerpt

The Cancer Genome Atlas (TCGA) Renal Phenotype Research Group is part of the

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For kidney cancer, TCGA will create a reference genome, against which new patients will be compared, for both clear cell and papillary cancer types. The initial objectives of TCGA for kidney cancer are, according to the NIH:

  • Identify unique patterns of genomic changes that divide clear cell and papillary carcinoma tumors into subgroups
  • Identify genomic differences that distinguish tumors across gender, race or ethnicity
  • Determine if specific patterns of genomic changes are connected to tumor recurrence after therapy

Research Group Participants

Oguz Akin, MD
Director, Body MRI,
Dept. of Radiology, MSKCC

Please contact the CIP Informatics Team if your research group would like to be kept in the loop as this effort moves forward. You can reach us by emailing John Freymann or Justin Kirby at:

  • freymanj (at) mail (dot) nih (dot) gov
  • kirbyju (at) mail (dot) nih (dot) gov

Data Providers

We would like to thank the following institutions for contributing images to the TCGA-GBM collection utilized in this research project:

  • MSKCC (in progress)

Related Shared Lists

  • None at this time

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Cancer Imaging Project TCGA Radiology Initiative; an effort to build a research community focused on connecting cancer phenotypes to genotypes by providing clinical images matched to tissue specimens analyzed for The Cancer Genome Atlas (TCGA).

Imaging Source Site (ISS) Groups are being formed and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, ISS groups are given the opportunity to publish a marker paper for a given cancer type per the guidelines in the table above. This opportunity will generate increased participation in building these multi-institutional data sets as they become an open community resource. Current TCGA-KIRC source sites include:

  • Memorial Sloan-Kettering Cancer Center
  • University of Pittsburgh / UPMC
  • Mayo
  • NCI Urologic Oncology Branch
  • UNC

Please contact Dr. Oguz Akin (akino@mskcc.org) if you have scientific questions for TCGA-KIRC ISS or are interested in collaborating with their group.

Publications

TCGA Renal Phenotype Research Group Publications

  • Shinagare AB, Vikram R, Jaffe C, Akin O, Kirby J, Huang E, Freymann J, Sainani NI, Sadow CA, Bathala TK, Rubin DL, Oto A, Heller MT, Surabhi VR, Katabathina V, Silverman SG. Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas-Renal Cell Carcinoma (TCGA-RCC) Imaging Research Group. Abdom Imaging. 2015 Aug;40(6):1684-92. doi: 10.1007/s00261-015-0386-z. (paper) (data)

Publications written by other members of the research community can be found on our TCIA Publications page.  Please contact us at help@cancerimagingarchive.net if you have a publication you would like us to add.

TCGA Genomics Publications

 Read the Nature paper about the TCGA-KIRC genomic study.  Additional TCGA publications can be found at: http://cancergenome.nih.gov/publications.

Publication Policies

 

Per TCGA and TCIA Guidelines, formal permission requests are no longer required to submit publications using TCGA-KIRC data.  Please see the following links for more information about the freedom-to-publish criteria for these data sets:

Data Source

Status

TCGA Data Portal Publication Guidelines

No restrictions; all data available without limitations.

TCIA Data Usage Policies and Restrictions

No restrictions; all data available without limitations.

Please contact us at help@cancerimagingarchive.net if you have any questions about these policies.