Summary

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For kidney cancer, TCGA will create a reference genome, against which new patients will be compared, for both clear cell and papillary cancer types. The initial objectives of TCGA for kidney cancer are, according to the NIH:

• Identify unique patterns of genomic changes that divide clear cell and papillary carcinoma tumors into subgroups
• Identify genomic differences that distinguish tumors across gender, race or ethnicity
• Determine if specific patterns of genomic changes are connected to tumor recurrence after therapy

For more information please contact us at cancerimagingarchive@mail.nih.gov .

Starting or Joining a Research Project

We are currently hosting calls in support of TCGA renal based research projects (TCGA-KIRC) on Fridays at 1pm Eastern. Please contact us at cancerimagingarchive@mail.nih.gov if you would like to inquire about setting up a new research project, discuss potential collaborations with existing groups or be otherwise kept in the loop as this effort moves forward.

Group Projects

This is a listing of ongoing projects.  If you are working with the TCGA glioma data hosted on TCIA please let us know and we would be happy to add a section describing your project here.

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Imaging Source Site (ISS) Groups are being formed and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, ISS groups are given the opportunity to publish a marker paper for a given cancer type per the guidelines in the table above. This opportunity will generate increased participation in building these multi-institutional data sets as they become an open community resource. Current The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma Collection (TCGA-KIRC) source sites include:

• Memorial Sloan-Kettering Cancer Center
• University of Pittsburgh / UPMC
• Mayo
• NCI Urologic Oncology Branch
• UNC

Please contact Dr. Oguz Akin (akino@mskcc.org) if you have scientific questions for TCGA-KIRC ISS or are interested in collaborating with their group.

Publications

TCGA Renal Phenotype Research Group Publications

• Shinagare AB, Vikram R, Jaffe C, Akin O, Kirby J, Huang E, Freymann J, Sainani NI, Sadow CA, Bathala TK, Rubin DL, Oto A, Heller MT, Surabhi VR, Katabathina V, Silverman SG. Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas-Renal Cell Carcinoma (TCGA-RCC) Imaging Research Group. Abdom Imaging. 2015 Aug;40(6):1684-92. doi: 10.1007/s00261-015-0386-z. (paper) (data)

Publications written by other members of the research community can be found on our TCIA Publications page.  Please contact us at help@cancerimagingarchive.net if you have a publication you would like us to add.

TCGA Genomics Publications

 Read the Nature paper about the TCGA-KIRC genomic study.  Additional TCGA publications can be found at: http://cancergenome.nih.gov/publications.

Publication Policies

Per TCGA and TCIA Guidelines, formal permission requests are no longer required to submit publications using TCGA-KIRC data.  Please see the following links for more information about the freedom-to-publish criteria for these data sets:

Please contact us at help@cancerimagingarchive.net if you have any questions about these policies.