Tuesday, Sept 25, 2012
On Phone:
Rajan, Laila (HF), Adam, Jim, Chad, Daniel R., Carl, John
- Rajan and Laila developing a new manuscript (walked through early results on call:
- Non-enhancing part of the lesion
- Next step – look at genomic pathways...
- rCBV-FL by non-enhancing region
- survival v. blood volume data
- low / high combining blood volume and edema for survival
- Blood volume data with vasari features
- Goal – show which is better or combined.
- Interesting results: changed plan a bit ....
- Correlate with non-enhancing lesions
- Correlation of survival data
- CBV in only the NON – enhancing part...
- Add the genomic information.
- Even w/o the genomics it is a manuscript
- Note – Rajan needs to process more perfusion cases... (beyond the initial 45)
- Jim Chen may have a fellow who could help
- JAMIA submissions from group ? No update
- Chad – Emory has new clinical Nordic Ice license – plan to leverage for new analysis
- May transfer NCI Nordic key to Jim Chen ..
- Chad – will combine some previous talks and present at Southeastern Neuroradiological Society:
- Overview
- Summarize of data from previous talks...
- RSNA meeting (Tues 5-6:30 pm at the Hilton)
- Adam will propose some topics – how do we move the field forward in genomics and imaging, What do you have to do to advance the field
- John will request Daoud to present next meeting.
Tuesday, September 11, 2012
On the phone:
Lisa, Erich, Jim, Ashley, Brad, Dave, John, Justin
Notes
- Dave Guttman radiology paper - some new statistical (will talk to Erich) and formatting comments / questions
- Dave is also finishing up a Jamia paper on pathology
- Reading status update by Justin:
- Latest goal: 31 cases being scored in the bunch
- Brad max manal prashant , jim – totally done with their reads (brad did an extra group)...
- still waiting on rivka, chad, and scott (who did three last week – in process of moving to St. Jude)...
- Rivka – 11 (9) to do
- Chad - 11 (minus the post-ops) = 7
- Scott has 6 to do
- Remaining unscored cases:
- ~45 on public from TJU
- ~40 in pipeline from Case Western (keep sequestered for possible Challenges?)
- LGG Cases
- Adam – went through the LGG cases from TJU (indicated which are post-op)...
- Do we want to start LGG now? / Or wait for Erich to do analysis on latest GBMs?
- LGG CRF:
- Dave – "keep the features, we have, and add the one (or two) features."
- need to decide if two new features or combine them
- Logic needed in the form because with the low-grades a lot of the questions won't be needed – (contrast enhancement will be rare)...
- Longest cross sectional area for enhancement won't exist, so do we want to measure something else – T2Flair (maximal cross sectional flair enhancement?)
- Dave – "keep the features, we have, and add the one (or two) features."
- Brad update on his in-house multi-vendor comparison – currently just going through patients to see who has progression / pseudo progression.