Summary
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The Cancer Genome Atlas (TCGA) Lung Phenotype Research Group is part of the |
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Cancer Imaging Program TCGA Radiology Initiative focused on analyzing images from the TCGA- |
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Lung Adenocarcinoma (LUAD) collection. Multiple modalities of images which correlate to the lung tissue data in |
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being gathered for submission to |
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The Cancer Imaging Archive (TCIA). |
According to the TCGA page on lung adenocarcinomaLUAD, researchers hope to make the following types of discoveries about lung adenocarcinoma ( LUAD ) and lung squamous cell carcinoma (LUSC):
- Pinpoint gene changes that divide squamous and adenocarcinoma tumors into molecular subgroups.
- Distinguish patterns of gene changes between adenocarcinoma and squamous cell carcinomaLUAD and LUSC.
- Distinguish genomic changes between smokers and non-smokers.
Starting or Joining a Research Project
We are not yet hosting calls in support of TCGA lung based research projects (TCGA-LUAD, TCGA-LUSC) but are currently looking for additional interested group members. Please contact us at cancerimagingarchive@mail.nih.gov if you would like to inquire about setting up a new research project, join an existing project, or be otherwise kept in the loop as this effort moves forward.
Group Projects
This is a listing of ongoing projects. If you are working with the TCGA lung data hosted on TCIA please let us know and we would be happy to add a section describing your project here.
- Coming soon
Publications
Research and Publications
Per TCGA and TCIA Guidelines, formal permission requests are still required to submit publications using TCGA-LUAD data. Please see the following links for more information about the freedom-to-publish criteria for these data sets:
Data Source | Status |
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No restrictions; all data available without limitations. | |
Projects have not reached 100 imaging cases; please check with help@cancerimagingarchive.net prior to any publication. |
Please contact us at help@cancerimagingarchive.net if you have any questions about these policies.
TCGA Lung Marker Paper and Image Source Sites (ISS)
Imaging Source Site (ISS) Groups will be populated and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, ISS groups are given the opportunity to publish a marker paper for a given cancer type per the guidelines in the table above. This opportunity will generate increased participation in building these multi-institutional data sets as they become an open community resource. Current TCGA-LUAD source sites include:
- Washington University in St. Louis
- UPMC
This group has not yet been established. We will provide a point of contact for the group from the ISS site(s) as soon as possible to address scientific questions or requests to collaborate with their groupThere are currently no imaging based publications for TCGA-LUAD or TCGA-LUSC that we are aware of. Please notify us at cancerimagingarchive@mail.nih.gov if you know of publications utilizing these TCIA collections.
References
The following links contain publications from the main TCGA project , as well as their posted publication guidelines.:
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TCGA 2nd Annual Symposium