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Presently, CIP is developing agreements with many of the TCGA Tissue Site Source institutions to recover and place in the Image Archive collections of diagnostic images that match the genomic data now being deposited in the publically accessible TCGA Data Portal on cancers of the brain (GBM/LGG), breast (BRCA), renal (KIRC), lung (LUAD), and in due time, many of the future 20-plus tumors that TCGA will characterize as the program moves forward.  Imaging Source Site (ISS) Groups are being created and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this will generate increased participation in the building of these multi-institutional data sets that become an open community resource. 

Publication Policies

TCIA publication guidelines are derived from the policy outlined by the The Cancer Genome Atlas. These must be followed in addition to the publication policy of the TCGA Data Portal: http://cancergenome.nih.gov/abouttcga/policies/publicationguidelines.

There are no limitations on publications containing analyses using any TCGA-linked imaging data set if the data set meets one of the following three freedom-to-publish criteria:

  1. A marker paper has been published on that tumor type; or
  2. 12 months after 100 cases of a given tumor type have had their DICOM data published on TCIA; or
  3. The author receives specific approval from the TCGA Image Source Site (ISS) Groups representing any relevant tumor types.

Imaging Source Site (ISS) Groups will be populated and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this will generate increased participation in the building of these multi-institutional data sets that become an open community resource.

Specifically, the status of each tumor data set is available below. If you have questions, do not hesitate to contact cancerimagingarchive@mail.nih.gov.

Tumor Type

Data Status

TCGA-GBM

No restrictions; image data available without limitations

TCGA-KIRC

Publication limitations in place until 08/22/2013

TCGA-BRCA

Publication limitations in place until 10/16/2013

TCGA-LUAD, TCGA-LGG

Projects have not reached 100 imaging cases; Please check with cancerimagingarchive@mail.nih.gov prior to any publication

Ongoing Research Efforts

Continuing these efforts CIP is working to enable ad hoc multi-institutional research teams for analysis of these data sets as they are collected. Efforts have already begun or are being initiated for the following TCGA tissue types:

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ISS only

TCGA-LUAD Phenotype Research Group

Lung adenocarcinoma (LUAD)

ISS only

TCGA-LGG Phenotype Research Group

Low grade glioma (LGG)

ISS only

TCGA-PRAD Phenotype Research Group

Prostate adenocarcinoma (PRAD)

ISS only

Please contact us at cancerimagingarchive@mail.nih.gov if you would like to

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join our public mailing lists to receive notifications of newly available data and other news items related to these data sets.

References

Included below are some posters and presentations which help summarize the CIP TCGA Radiology Initiative and its supporting components such as TCIA.

TCGA Publications and Publication Guidelines

The following links contain publications from the main TCGA project, as well as their posted publication guidelines.

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