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Summary

Excerpt

The

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Cancer Genome Atlas (TCGA) Ovarian Phenotype Research Group is part of the

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Cancer Imaging Project TCGA Radiology Initiative; an effort to build a research community focused on

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According to the TCGA page on Prostate Adenocarcinoma, researchers hope to make the following types of discoveries with this data:

  • Analyze correlation between Gleason score and other tumor characteristics to better define aggressiveness
  • Examine samples from majority populations and compare to underrepresented populations, such as African Americans who have the highest incidence rate of prostate cancer
  • Integrate the genomic information with the proteomic data

Research and Publications

Per TCGA and TCIA Guidelines formal permission requests are still required to submit publications using TCGA-OV data.  Please see the following links for more information about the freedom-to-publish criteria for these data sets:

Data Source

Status

TCGA Data Portal Publication Guidelines

Project has reached 570 cases; Please check with TCGA prior to any publication

TCIA Data Usage Policies and Restrictions

Projects have not reached 100 imaging cases; Please check with cancerimagingarchive@mail.nih.gov prior to any publication

Please contact us at cancerimagingarchive@mail.nih.gov if you have any questions about these policies, or would like to join our public mailing list and be kept in the loop about new data releases and other related news as this effort moves forward.

TCGA-OV Marker Paper and Image Source Sites (ISS)

connecting cancer phenotypes to genotypes by providing clinical images matched to tissue specimens analyzed for The Cancer Genome Atlas (TCGA).

Imaging Source Site (ISS) Groups will be populated are being formed and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these ISS groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this type per the guidelines in the table above. This opportunity will generate increased participation in the building of these multi-institutional data sets that as they become an open community resource.  Current  Current TCGA-OV source  source sites include:

  • Washington University St. Louis
  • MSKCC
  • UPMC
  • MDACC
  • UNC

Please contact Dr. Evis Sala (salae@mskccsalae@mskcc.org) if you have scientific questions you would like to direct to the for TCGA-OV ISS, or are interested in collaborating with their group.

References

The following links contain publications from the main TCGA project, as well as their posted publication guidelines.

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Publications

TCGA Ovarian Phenotype Research Group Publications

  • Vargas HA, Huang EP, Lakhman Y, Ippolito JE, Bhosale P, Mellnick V, Shinagare AB, Anello M, Kirby J, Fevrier-Sullivan B, Freymann J, Jaffe CC, Sala E. Radiogenomics of High-Grade Serous Ovarian Cancer: Multireader Multi-Institutional Study from the Cancer Genome Atlas Ovarian Cancer Imaging Research Group. Radiology. 2017 Jun 22:161870. doi: 10.1148/radiol.2017161870. (link)

Publications written by other members of the research community can be found on our TCIA Publications page.  Please contact us at help@cancerimagingarchive.net if you have a publication you would like us to add.

TCGA Genomics Publications

 Read about the TCGA-OV genomic study.  Additional TCGA publications can be found at: http://cancergenome.nih.gov/publications.

Publication Policies

 

Per TCGA and TCIA Guidelines, formal permission requests are no longer required to submit publications using TCGA-OV data.  Please see the following links for more information about the freedom-to-publish criteria for these data sets:

 

Data Source

Status

TCGA Data Portal Publication Guidelines

No restrictions; all data available without limitations.

TCIA Data Usage Policies and Restrictions

No restrictions; all data available without limitations.

 

Please contact us at help@cancerimagingarchive.net if you have any questions about these policies.