Summary

This collection contains “double baseline” multi-parametric MRI images collected on patients with newly diagnosed glioblastoma.  The value of this collection is to provide clinical image data to establish the test-retest characteristics of parameters calculated from DW-MRI, DCE-MRI, and DSC-MRI such as ADC, Ktrans and rCBV. Data were provided by Dr. Elizabeth Gerstner and Dr. Kalpathy-Cramer (MGH) as part of their participation in the Quantitative Imaging Network.

The patients were scanned after surgery but prior to the start of therapy, typically 2-5 days apart. The structural images included T1-weighted pre- and post-contrast images, T2-weighted images, FLAIR and MEMPRAGE images.  Advanced MRI sequences included Diffusion Weighted (DW) Imaging, Dynamic Contrast-Enhanced MRI (DCE-MRI), and Dynamic Susceptibility Contrast MRI (DSC-MRI).  

Note: If there was an issue with the scan it was excluded, so not all patients have every type of scan available.

The images were obtained on 32-channel Siemens Trio 3T scanners using Siemens 32-channel head coils.

About the NCI QIN

The mission of the QIN is to improve the role of quantitative imaging for clinical decision making in oncology by developing and validating data acquisition, analysis methods, and tools to tailor treatment for individual patients and predict or monitor the response to drug or radiation therapy. More information is available on the Quantitative Imaging Network Collections page. Interested investigators can apply to the QIN at: Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01) PAR-11-150.



Data Access

Data TypeDownload all or Query/FilterLicense
Images (DICOM, 33.5 GB)







(Download requires the NBIA Data Retriever)



Click the Versions tab for more info about data releases.


Detailed Description

Collection Statistics


Modalities

 MR

Number of Patients

 54

Number of Studies

 106

Number of Series

 1,942

Number of Images

 589,314

Images Size (GB) 33.5


NOTE: If you use the Dynamic Susceptibility Contrast MRI (DSC-MRI) portion of these data, please cite the Collection by DOI, as well as both of the following articles as sources:

  1. Prah MA, Stufflebeam SM, Paulson ES, Kalpathy-Cramer J, Gerstner ER, Batchelor TT, Barboriak DP, Rosen BR, Schmainda KM. (2015). Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma. American Journal of Neuroradiology. American Society of Neuroradiology (ASNR). DOI: 10.3174/ajnr.a4374 
  2. Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM. (2015). Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients. Translational Oncology. Elsevier BV. DOI: 10.1016/j.tranon.2015.03.002



Citations & Data Usage Policy 

Mamonov AB, Kalpathy-Cramer J. (2016). Data From QIN GBM Treatment Response. The Cancer Imaging Archive. DOI: 10.7937/k9/tcia.2016.nQF4gpn2


Prah MA, Stufflebeam SM, Paulson ES, Kalpathy-Cramer J, Gerstner ER, Batchelor TT, Barboriak DP, Rosen BR, Schmainda KM. (2015). Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma. American Journal of Neuroradiology. American Society of Neuroradiology (ASNR). DOI: 10.3174/ajnr.a4374 


Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM. (2015). Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients. Translational Oncology. Elsevier BV. DOI: 10.1016/j.tranon.2015.03.002


Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. DOI: 10.1007/s10278-013-9622-7

Other Publications Using This Data

TCIA maintains a list of publications that leverage our data.  If you have a manuscript you'd like to add, please contact TCIA's Helpdesk.


Version 2 (Current): Updated 2020/04/03

Data TypeDownload all or Query/Filter
Images (DICOM, 33.5GB)






(Download requires the NBIA Data Retriever)

Lifted access embargo.

Version 1 : Updated 2015/08/12

Data TypeDownload all or Query/Filter
Images (DICOM, 33.5GB)




(Download requires the NBIA Data Retriever)