This data collection consists of MRI/CT scan data for brain tumor patients that form the cohort for the resource Ivy Glioblastoma Atlast Project (Ivy GAP) as summarized below. There are 399 scans for 41 patients that include pre-surgery, post-surgery and follow up scans.
The Ivy Glioblastoma Atlas Project (Ivy GAP) is a collaborative partnership between the Ben and Catherine Ivy Foundation, which generously provided the financial support, the Allen Institute for Brain Science, and the Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment. The goal of the project is to provide online resources to scientists and physicians dedicated to the development of innovative treatments and diagnostics that will enhance the quality of life and survival of patients with brain cancer.
These resources represent an unprecedented platform for exploring the anatomic and genetic basis of glioblastoma at the cellular and molecular levels. They include two interactive databases linked together by de-identified tumor specimen numbers to facilitate comparisons across data modalities:
• The open public image database on www.brain-map.org providing in situ hybridization (ISH) and RNA sequencing (RNA-Seq) data, which map gene expression across the anatomic structures and putative cancer stem cell clusters in glioblastoma. The associated histological dataset is annotated and is suitable for neuropathological examination.
• A companion database (Ivy GAP Clinical and Genomic Database) offering detailed clinical, genomic, and expression array data sets that are designed to elucidate the pathways involved in glioblastoma development and progression. This database requires registration for access.
The hope is that researchers will mine these data and identify trends, correlations, and interesting leads for further studies with significant translational and clinical outcomes.
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