Imaging data from clinical trials provides the opportunity to  link imaging characteristics to clinical trial analyses, associated clinical data and patient outcomes.  Beginning in 2019, the NCI Cancer Imaging Program Informatics Lab is supporting an additional TCIA  image data collection center focused specifically on clinical trial data.   Many TCIA clinical trial data sets will originate from the NCI National Clinical Trials Network (NCTN), which is a collection of organizations and clinicians that coordinates and supports cancer clinical trials at more than 3,000 sites across the United States and Canada. The NCTN provides the infrastructure for NCI-funded treatment, screening, and diagnosis trials to improve the lives of patients with cancer.  The NCTN explicitly requires data sharing of the patient-level clinical data in https://nctn-data-archive.nci.nih.gov/view-trials, and TCIA serves as the imaging repository for that archive.

Clinical Trial Datasets on TCIA


Collection NameClinicalTrials.gov ID
1ACRIN-HNSCC-FDG-PET/CT (ACRIN 6685)NCT00983697 
2ACRIN-DSC-MR-Brain (ACRIN 6677/RTOG 0625)NCT00433381 
3NSCLC-Cetuximab (RTOG-0617)NCT00533949 
4ACRIN-NSCLC-FDG-PET (ACRIN 6668)NCT00083083 
5ACRIN-FMISO-Brain (ACRIN 6684)NCT00902577 
6ACRIN-FLT-Breast (ACRIN 6688)NCT00572728
7ISPY1 (ACRIN 6657)NCT00043017
8NRG-1308 (RTOG 1308)NCT01993810
9National Lung Screening TrialNCT00047385
10Head-Neck Cetuximab (RTOG 0522)NCT00265941 
11CT Colonography (ACRIN 6664)NCT00084929