RIDER Neuro MRI contains imaging data on 19 patients with recurrent glioblastoma who underwent repeat imaging sets.  These images were obtained approximately 2 days apart (with the exception of one patient, RIDER Neuro MRI-1086100996, whose images were obtained one day apart).   

DCE‐MRI:  All 19 patients had repeat dynamic contrast‐enhanced MRI (DCE‐MRI) datasets on the same 1.5T imaging magnet.  On the basis of T2‐weighted images, technologists chose 16 image locations using 5mm thick contiguous slices for the imaging.  For T1 mapping, multi‐flip 3D FLASH images were obtained using flip angles of 5, 10, 15, 20, 25 and 30 degrees, TR of 4.43 ms, TE of 2.1 ms, 2 signal averages.  Dynamic images were obtained during the intravenous injection of 0.1mmol/kg of Magnevist intravenous at 3ccs/second, started 24 seconds after the scan had begun.  The dynamic images were acquired using a 3D FLASH technique, using a flip angle of 25 degrees, TR of 3.8 ms, TE of 1.8 ms using a 1 x1 x 5mm voxel size.  The 16 slice imaging set was obtained every 4.8 sec.

DTI: Seventeen of the 19 patients also obtained repeat diffusion tensor imaging (DTI) sets.  Whole brain DTI were obtained using TR 6000ms, TE 100 ms, 90 degree flip angle, 4 signal averages, matrix 128 x 128,  1.72 x 1.72 x 5 mm voxel size, 12 tensor directions, iPAT 2, b value of 1000 sec/mm2 .

Contrast‐enhanced 3D FLASH: All 19 patients underwent whole brain 3D FLASH imaging in the sagittal plane after the administration of Magnevist.  For this sequence, TR was 8.6 ms, TE 4.1 ms, 20 degree flip angle, 1 signal average, matrix 256 x 256; 1mm isotropic  voxel  size.

Contrast‐enhanced 3D FLAIR: All 17 patients who had repeat DTI sets also had 3D FLAIR sequences in the sagittal plane after the administration of Magnevist.  For this sequence, the TR was 6000 ms, TE 353 ms, and TI 2200ms; 180 degree flip angle, 1 signal average, matrix 256 x 216; 1 mm isotropic voxel size. Note: before transmission to NCIA, all image sets with 1mm isotropic voxel size were “defaced” using MIPAV software or manually.


Data Access

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DICOM Metadata Digest (CSV)

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Detailed Description

Collection Statistics




Number of Patients


Number of Studies


Number of Series


Number of Images


Image Size (GB)7.3

Pages 19-22 (Appendix 2) of the RIDER White Paper: Combined contracts report ( Sept 2008) PDF cover this data set in great detail.

Citations & Data Usage Policy 

This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License.  See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to

Please be sure to include the following citations in your work if you use this data set:

Barboriak, Daniel. (2015). Data From RIDER_NEURO_MRI. The Cancer Imaging Archive.

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)


Other Publications Using This Data


TCIA maintains a list of publications which leverage our data. At this time we are not aware of any additional publications based on this data. If you have a publication you'd like to add please contact the TCIA Helpdesk.

Version 1 (Current): Updated 2011/11/08

Downloads require the NBIA Data Retriever.

Data TypeDownload all or Query/Filter
Images (DICOM, 7.3GB)


DICOM Metadata Digest (CSV)