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Images (DICOM, 2.3 GB) | | Supplemental Data (format) | |
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Detailed Description
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Modalities | MR | Number of Subjects | 20 | Number of Studies | 115 | Number of Series | 210 | Number of Images | 3509 | Images Size (GB) | 2.3 GB |
# animals in group | # animals that displayed metastasis in MRI and confirmed by Pathology | Pathology confirmation of MRI (primary imaging site) | Other confirmed Location (s) |
10 (non-resected) | 6 (4 mice were EU due to xenograft size prior to observation of metastasis) | Lung | Lymph node | 10 (resected) | 10 | Lung | Lymph node |
Percent penetrance with respect to the average time-to-metastasis for non-resected (plot A: time from implant) and resected (plot B: time from tumor resection) cohorts. Plot A Plot B PET/CT Characterization of the primary tumor: Baseline PET (SOP attached) were performed when tumor reached an approximate 200 mm3. Average SUVmax values (n=5) were calculated; [18F]FDG: 2.7 ± 0.5 and [18F]FLT: 2.0 ± 0.3.
Conclusion: Melanoma PDMR-425362-245-T model can be challenging due to the rapid growth of the xenograft and regrowth. Metastases was well observed on T2 MRI imaging allowing non-invasive evaluation in treatment trials. |
Citations & Data Usage PolicyThese collections are freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. Questions may be directed to help@cancerimagingarchive.net. Please be sure to acknowledge both this data set and TCIA in publications by including the following citations in your work: Tatum, J. L., (https://orcid.org/0000-0002-3217-2478) Kalen, J. D., (https://orcid.org/0000-0002-7163-4604) Jacobs, P. M., (https://orcid.org/0000-0002-9423-6473) Ileva, L. V., (https://orcid.org/0000-0001-8286-8396) Riffle, L. A., (https://orcid.org/0000-0003-3975-3088) Keita, S., Patel, N., (https://orcid.org/0000-0002-8251-7155) Sanders, C., (https://orcid.org/0000-0001-8042-4783) James, A., Difilippantonio, S., (https://orcid.org/0000-0002-8234-1559) Thang, L. Hollingshead, M. G., (https://orcid.org/0000-0002-1207-1397) Phillips, J., Edmondson, E https://orcid.org/0000-0002-6106-3705 Evrard, Y., Clunie, D. A, (https://orcid.org/0000-0002-2406-1145) Liu, Y., Smith, K. E, (https://orcid.org/0000-0002-8735-7576) Wagner, U., (https://orcid.org/0000-0002-3230-5058) Freymann, J. B. Kirby, J., https://orcid.org/0000-0003-3487-8922) Doroshow, J. H, (https://orcid.org/0000-0002-4463-1790) |
This project has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, under Contract No. HHSN261201500003I. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. |
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. DOI: https://doi.org/10.1007/s10278-013-9622-7 |
Other Publications Using This DataTCIA maintains a list of publications which leverage TCIA data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk. |
Version 1 (Current): Updated yyyy/mm/ddData Type | Download all or Query/Filter |
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Images (DICOM, 2.3 GB) | | Clinical Data (CSV) | Link | Other (format) | |
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