Summary

These retrospective NIfTI image datasets consists of unenhanced chest CTs: 

  • First dataset - from 632 patients with COVID-19 infections at initial point of care, and
  • Second dataset - a second set of 121 CTs from 29 patients with COVID-19 infections with serial / sequential CTs.

The initial images for both datasets were acquired at the point of care in an outbreak setting from patients with Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmation for the presence of SARS-CoV-2.

Patients presented to a health care setting with a combination of symptoms, exposure to an infected patient, or travel history to an outbreak region. All patients had a positive RT-PCR for SARS-CoV-2 from a sample obtained within 1 day of the initial CT. CT exams were performed without intravenous contrast and with a soft tissue reconstruction algorithm.  The DICOM images were subsequently converted into NIfTI format. The second dataset also had other follow up CTs, in addition to the initial point of care CT.

A multidisciplinary team trained several models using portions of the first dataset, along with additional CTs and manually annotated images from other sources. A classification model derived in part from the first dataset is described in a Nature Communications manuscript at:  https://doi.org/10.1038/s41467-020-17971-2The NVIDIA-related frameworks and models specific to this publication are available at no cost as part of the NVIDIA Clara Train SDK at https://ngc.nvidia.com/catalog/containers/nvidia:clara:ai-covid-19This includes both inference-based pipelines for evaluation, as well as model weights for further training or fine tuning in outside institutions. The second data set of 121 serial / sequential CTs in 29 patients is reported in a Scientific Reports manuscript at  https://doi.org/10.1038/s41598-021-85694-5

Acknowledgements

The Imaging AI in COVID team would like to acknowledge the following individuals who supported this multi-disciplinary multi-national team effort:

TCIA COVID-19 Datasets

Additional datasets and information about TCIA efforts to support COVID-19 research can be found here.


Data Access

Data TypeDownload all or Query/FilterLicense

Images (NIfTI, 12.71 GB)

First dataset




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Images (NIfTI, 2 GB)

Second dataset



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Detailed Description

Image Statistics


Modalities

CT

Number of Patients

661

Number of Series

771
Images Size (GB)14.7


Link to publication below contains AI model that was only partly derived from this data, and also from other data not present here on TCIA.

  • Harmon, S. A., Sanford, T. H., Xu, S., Turkbey, E. B., Roth, H., Xu, Z., Yang, D., Myronenko, A., Anderson, V., Amalou, A., Blain, M., Kassin, M., Long, D., Varble, N., Walker, S. M., Bagci, U., Ierardi, A. M., Stellato, E., Plensich, G. G., Franceschelli, G., Girlando, C., Irmici, G., Labella, D., Hammoud, D., Malayeri, A., Jones, E., Summers, R. M., Choyke, P.L., Xu, D., Flores, M., Tamura, K., Obinata, H., Mori, H., Patella, F., Cariati, M., Carrafiello, G., An, P., Wood, B. J., & Turkbey, B. (2020). Artificial intelligence for the detection of COVID-19 pneumonia on chest CT using multinational datasets. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-17971-2


Citations & Data Usage Policy

An, P., Xu, S., Harmon, S. A., Turkbey, E. B., Sanford, T. H., Amalou, A., Kassin, M., Varble, N., Blain, M., Anderson, V., Patella, F., Carrafiello, G., Turkbey, B. T., & Wood, B. J. (2020). CT Images in COVID-19 [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/TCIA.2020.GQRY-NC81


The Multi-national NIH Consortium for CT AI in COVID-19.


Harmon, S. A., Sanford, T. H., Xu, S., Turkbey, E. B., Roth, H., Xu, Z., Yang, D., Myronenko, A., Anderson, V., Amalou, A., Blain, M., Kassin, M., Long, D., Varble, N., Walker, S. M., Bagci, U., Ierardi, A. M., Stellato, E., Plensich, G. G., Franceschelli, G., Girlando, C., Irmici, G., Labella, D., Hammoud, D., Malayeri, A., Jones, E., Summers, R. M., Choyke, P.L., Xu, D., Flores, M., Tamura, K., Obinata, H., Mori, H., Patella, F., Cariati, M., Carrafiello, G., An, P., Wood, B. J., & Turkbey, B. (2020). Artificial intelligence for the detection of COVID-19 pneumonia on chest CT using multinational datasets. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-17971-2


Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. Journal of Digital Imaging, 26(6), 1045–1057. https://doi.org/10.1007/s10278-013-9622-7



Other Publications Using This Data

TCIA maintains a list of publications which leverage our data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.


Version 2 (Current): Updated 2021/05/25

Data TypeDownload all or Query/Filter

Images (NIfTI, 12.71 GB)

First dataset




Images (NIfTI, 2 GB)

Second dataset




Added second dataset, 29 patients/121 CT images.

Version 1: Updated 2020/08/31

Data TypeDownload all or Query/Filter

Images (NIfTI, 12.71 GB)