This collection contains a labelled dataset of MRI images collected on 246 consecutive patients with vestibular schwannoma undergoing Gamma Knife stereotactic radiosurgery (GK SRS). The structural images included contrast-enhanced T1-weighted (ceT1) images and high-resolution T2-weighted (hrT2) images. Each imaging dataset is accompanied by the patient’s radiation therapy (RT) dataset including the RTDose, RTStructures and RTPlan. All structures were manually segmented in consensus by the treating neurosurgeon and physicist using both the ceT1 and hrT2 images. The value of this collection is to provide clinical image data including fully annotated tumour segmentations to facilitate the development and validation of automated segmentation frameworks. It may also be used for research relating to radiation
Data were obtained from the Queen Square Radiosurgery Centre (Gamma Knife). Imaging data from consecutive patients with a single sporadic VS treated with GK SRS between October 2012 and January 2018 were screened for the study. All adult patients older than 18 years with a single unilateral VS treated with GK SRS were eligible for inclusion in the study, including patients who had previously undergone operative surgical treatment. In total, 248 patients met these initial inclusion criteria including 51 patients who had previously undergone surgery. Patients were only included in the study if their pre-treatment image
All manual segmentations were performed using Gamma Knife planning software (Leksell GammaPlan, Elekta, Sweden) that employs an in-plane semiautomated segmentation method. Using this software, each axial slice was manually segmented in turn.
We would like to acknowledge the individuals and institutions that have provided data for this collection: This work was supported by Wellcome Trust (203145Z/16/Z, 203148/Z/16/Z, WT106882) and EPSRC (NS/A000050/1, NS/A000049/1) funding. Tom Vercauteren is also supported by a Medtronic/Royal Academy of Engineering Research Chair (RCSRF1819\7\34).
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