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- Overview, study design, recruitment methods, endpoint verification process (determining cause of death), quality control (LSS and ACRIN).
- LSS Manual of Operations (MOOP) and ACRIN Protocol.
- DSMB announcement of results (10/28/2010).
https://biometry.nci.nih.gov/cdas/nlst/learn/main_findings
NLST Publications and Projects
- Primary Results, Study Design, Feasibility Study for the NLST, Psychosocial and Behavioral Issues, Technical Publications.
http://www.cancer.gov/clinicaltrials/noteworthy-trials/nlst/publications-from-nlst
- Browse Publications, browse projects, search.
https://biometry.nci.nih.gov/cdas/nlst/pubs_projects
NLST Data Collected
- Questionnaires, screening, diagnostic procedures, cancer diagnosis, treatment, progression, mortality, contamination.
https://biometry.nci.nih.gov/cdas/nlst/learn/data_collected
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- Directly from IMS
Investigators with an approved request may download comprehensive NLST datasets directly from the CDAS website. Datasets are provided in SAS format in one compressed file (.zip); other formats are available upon request. - Indirectly, through the Query Tool (QT): NLST Database Query Tool
Investigators launch the web-based QT, make menu-driven queries against the QT database (a significant subset of all trial data), and save query results to an Excel spreadsheet. The chief advantage to the QT is the ability to rapidly adjust queries and build a final spreadsheet for analysis. In addition, the QT offers the ability to download associated CT image
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For general details about the CT images, see NLST Images -- General Details
Pathology images: A small number (~1,250) of lung-biopsy pathology images are viewable using caMicroscope which is launched by the Query Tool.
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