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Sparsely Annotated Region and Organ Segmentation (SAROS) contributes a large heterogeneous semantic segmentation annotation dataset for existing CT imaging cases on TCIA. The goal of this dataset is to provide high-quality annotations for building body composition analysis tools (see [Koitka 2020: https://doi.org/10.1007/s00330-020-07147-3]). Existing in-house segmentation models were employed to generate annotation candidates on randomly selected cases. All generated annotations were manually reviewed and corrected by medical residents and students on every fifth axial slice while other slices were set to an ignore label (numeric value 255).

900 sample cases, 450 female and 450 male, CT series from 882 patients were randomly selected from the following TCIA collections (number of cases CTs per collection in parenthesis):    ACRIN-FLT-Breast (32), ACRIN-HNSCC-FDG-PET/CT (48), ACRIN-NSCLC-FDG-PET (129), Anti-PD-1_Lung (12), Anti-PD-1_MELANOMA (2), C4KC-KiTS (175), COVID-19-NY-SBU (1), CPTAC-CM (1), CPTAC-LSCC (3), CPTAC-LUAD (1), CPTAC-PDA (8), CPTAC-UCEC (26), HNSCC (17), Head-Neck Cetuximab (12), LIDC-IDRI (133), Lung-PET-CT-Dx (17), NSCLC Radiogenomics (7), NSCLC-Radiomics (56), NSCLC-Radiomics-Genomics (20), Pancreas-CT (58), QIN-HEADNECK (94), Soft-tissue-Sarcoma (6), TCGA-HNSC (1), TCGA-LIHC (33), TCGA-LUAD (2), TCGA-LUSC (3), TCGA-STAD (2), TCGA-UCEC (1).

A script to download and resample the images is provided in our GitHub repository: https://github.com/UMEssen/saros-dataset

The annotations are provided in NIfTI format and were performed on 5mm slice thickness. The annotation files define foreground labels on the same axial slices and match pixel-perfect. In total, 13 semantic body regions and 6 body part part labels were annotated with an index that corresponds to a numeric value in the segmentation file. 

Body Regions

1. Subcutaneous Tissue
2. Muscle
3. Abdominal Cavity
4. Thoracic Cavity
5. Bones
6. Parotid Glands
7. Pericardium
8. Breast Implant
9. Mediastinum
10. Brain
11. Spinal Cord
12. Thyroid Glands
13. Submandibular Glands

Body Parts

1. Torso
2. Head
3. Right Leg
4. Left Leg
5. Right Arm
6. Left Arm

The labels which were modified or require further commentary are listed and explained below:

• Subcutaneous Adipose Tissue: The cutis was included into this label due to its limited differentiation in 5mm-CT.
• Muscle: All muscular tissue was segmented contiguously and not separated into single muscles. Thus, fascias and intermuscular fat were included into the label. Inter- and intramuscular fat is subtracted automatically in the process.
• Abdominal Cavity: This label includes the pelvis. The label does not separate between the positional relationships of the peritoneum.
• Mediastinum: The International Thymic Malignancy Group (ITMIG) scheme was used for the segmentation guidelines.
• Head + Neck: The neck is confined by the base of the trapezius muscle.
• Right + Left Leg: The legs are separated from the torso by the line between the two lowest points of the Rami ossa pubis.
• Right + Left Arm: The arms are separated from the torso by the diagonal between the most lateral point of the acromion and the tuberculum infraglenoidale.

For reproducibility on downstream tasks, five cross-validation folds and a test set were pre-defined and are described in the provided spreadsheet. Segmentation was conducted strictly in accordance with anatomical guidelines and only modified if required for the gain of segmentation efficiency. 

Benefit to Researchers: Researchers can build upon this data to develop fully automated body composition analysis pipelines or use this data for different purposes in medical image segmentation.