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  • Tumor-Infiltrating Lymphocytes Maps from TCGA H&E Whole Slide Pathology Images (TIL-WSI-TCGA)

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titleDataset Citation

Saltz, J., Gupta, R., Hou, L., Kurc, T., Singh, P., Nguyen, V., … Thorsson, V. (2018). Tumor-Infiltrating Lymphocytes Maps from TCGA H&E Whole Slide Pathology Images [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/k9/tcia.2018.y75f9w1

Description

Mappings of tumor-infiltrating lymphocytes (TILs), based on H&E images from 13 TCGA tumor types are available here. These TIL maps are derived through computational staining, using a convolutional neural network trained to classify patches of images. In addition to the TIL Maps, the analysis codes and the software used to extract TILs are also available. The accompanying paper contains detailed information about our methods and our findings.

TCGA Tumor Types Used in this Study

BLCABladder urothelial carcinoma
BRCABreast invasive carcinoma
CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
COADColon adenocarcinoma
LUADLung adenocarcinoma
LUSCLung squamous cell carcinoma
PAADPancreatic adenocarcinoma
PRADProstate adenocarcinoma
READRectum adenocarcinoma
SKCMSkin Cutaneous Melanoma
STADStomach adenocarcinoma
UCECUterine Corpus Endometrial Carcinoma
UVMUveal Melanoma


Localtab Group


Localtab
activetrue
titleData Access

Data Access

Click the Download button to save a ".tcia" manifest file to your computer, which you must open with the NBIA Data Retriever

Data TypeDownload all or Query/Filter
TIL Maps
Clinical Data
H&E Images

Note:  Please contact help@cancerimagingarchive.net  with any questions regarding usage.


Localtab
titleDetailed Description

Detailed Description


Localtab
titleCitations & Data Usage Policy

Citations & Data Usage Policy 

These collections are freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. Questions may be directed to help@cancerimagingarchive.net. Please be sure to acknowledge both this data set and TCIA in publications by including the following citations in your work:

Info
titleData Citation

Saltz, J., Gupta, R., Hou, L., Kurc, T., Singh, P., Nguyen, V., … Thorsson, V. (2018). Tumor-Infiltrating Lymphocytes Maps from TCGA H&E Whole Slide Pathology Images [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/k9/tcia.2018.y75f9w1


Info
titleTCIA Citation

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)

In addition to the dataset citation above, please be sure to cite the following if you utilize these data in your research:

Info
titlePublication Citation

Saltz, J., Gupta, R., Hou, L., Kurc, T., Singh, P., Nguyen, V., . . . Thorsson, V.

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Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Reports, 23(1), 181-193.e187. https://doi.org/10.1016/j.celrep.2018.03.086

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Note:  Please contact help@cancerimagingarchive.net  with any questions regarding usage.

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Other Publications Using This Data

TCIA maintains a list of publications that leverage TCIA data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.


Localtab
titleVersions

Version 1 (Current): 2019/08/02

Data TypeDownload all or Query/Filter
TIL Maps
Clinical Data

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H&E Images

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