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This dataset contains image annotations derived from the NCI Clinical Trial "Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma (AHOD0831)”. The key objective of this project is to generate a large and highly curated imaging dataset of pediatric Hodgkin lymphoma patients with annotations suitable This dataset was generated as part of an NCI project to augment TCIA datasets with annotations that will improve their value for cancer researchers and AI developers. from proposal form (needs revision): The annotation protocol consists of longitudinal volumetric segmentations and seed points of neoplastic lymph nodes and tumor. The annotation protocol closely aligns with the baseline and followup imaging design of the AHOD0831 clinical trial. The goal of the annotation protocol is to provide consistent and detailed therapy response assessment. The volumetric segmentations are provided in DICOM Segmentation format and seed points (kernels) are provided as POINT structures in DICOM RTSS format. Annotation of imaging sequences was chosen with maximum clinical utility in mind. The neoplastic lymph nodes and areas of tumor were annotated on the attenuation correct PET as well as the post contrast axial series. If post contrast imaging was not avialble, the axial non contrast CT series was used.Annotation ProtocolFor each patient, every DICOM Study and DICOM Series was reviewed to identify and annotate the clinically relevant time points and sequences/series. In a typical patient all available time points were annotated: In a typical patient the following annotation rules were followed:
At each time point:
Important supplementary information and sample code
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