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Imaging time points: MRI exams were performed within four weeks prior to starting anthracycline-cyclophosphamide chemotherapy (T1, MRI1), at least 2 weeks after the first cycle of AC and prior to the second cycle of AC (T2, MRI2), between anthracycline-cyclophosphamide treatment and taxane therapy if taxane was administered (T3, MRI3), and after the final chemotherapy treatment and prior to surgery (T4, MRI4). The study schema is shown in Figure 1
Figure 1. I-SPY 1 TRIAL CALGB 150007 and ACRIN 6657 study schema.
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This is a limited access data set. To request access, please contact submit a concept sheet ((((link to ACRIN doc.))) to (ACRIN Contact). If access is granted you will be able to view and download these images on The Cancer Imaging Archive (TCIA) by logging in and selecting the I-SPY1 collection. This data set will be made publicly available on or before XXXX XX, 20XX. |
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This shared data set was provided by the Breast Imaging Research Program at UCSF, in collaboration with ACRIN, the Iwith ACRIN, CALGB, the I-SPY TRIAL, and TCIA.
David Newitt, PhD, UCSF, Nola Hylton, PhD, UCSF
Funding sources include:
| UCSF | NIH R01 CA132870 and U01 CA151235 |
| ACRIN | NIH UO1 CA079778 and UO1 CA080098 |
| I-SPYCALGB | NIH UO1 CA31964 and UO1 CA33601 |
((( Insert full acknowledgement lists here )))
Thanks to:
- The ACRIN 6657 trial team (((MAKE LINK TO FULL LIST )))
- The I-SPY 1 TRIAL team (((MAKE LINK TO FULL LIST )))
- All the patients participating in these studies
((( END OF PUBLIC PAGE - REST GOES ON SEPARATE PAGE ACCESSIBLE TO THOSE WITH STUDY DOWNLOAD PRIVILEDGES )))
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I-SPY 1 / ACRIN 6657 - Collection Description
If you are unsure how to download this Collection please view Searching by Collection or refer to The Cancer Imaging Archive User's Guide for more detailed instructions on using the site.
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The processing of the MR image data for ACRIN 6657 / I-SPY 1 consisted of the following steps between image acquisition and the creation of this shared data set on TCIA:
- MRI studies were sent from the study centers to the ACRIN Core Lab either via media (DVD) or the TRIAD program
- Image data were de-identified and centrally archived at the ACRIN Core Lab
- Archived data was sent to the breast MR imaging laboratory research program (BIRP) at the University of California at , San Francisco (UCSF) for volumetric analysis.
- De-identified image data, derived analysis maps and segmentations, and ancillary data files were transferred from UCSF to TCIA for data sharing.
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