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Summary
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The National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) is a national effort to accelerate the understanding of the molecular basis of cancer through the application of large-scale proteome and genome analysis, or proteogenomics. Radiology and pathology images from CPTAC Phase 3 patients are being collected and made publicly available by The Cancer Imaging Archive to enable researchers to investigate cancer phenotypes which may correlate to corresponding proteomic, genomic and clinical data. |
Pathology imaging is collected as part of the CPTAC qualification workflow. Radiology imaging is collected from standard of care imaging performed on patients immediately before the pathological diagnosis, and from follow-up scans where available. For this reason the radiology image data sets are heterogeneous in terms of scanner modalities, manufacturers and acquisition protocols.
CPTAC Phase 3 collects data from ten cancer types. In TCIA, imaging from each cancer type will be contained in its own TCIA Collection, with the collection name "CPTAC-cancertype". This collection addresses CPTAC participants with pancreatic ductal adenocarcinoma (PDA). CPTAC Phase 3 Imaging data is made available on TCIA each quarter as it is collected.
Acknowledgements
We would like to acknowledge the individuals and institutions that have provided data for this collection:
- Beaumont Health System, Royal Oak, MI - Special thanks to George D. Wilson, PhD from the Department of Radiation Oncology Research, Barbara Pruetz of the Biobank, Debra Kapczynski, MHSA, CIIP, RT(R)(CT) and Rachel Deyer from the Department of Diagnostic Radiology.
- International Institute for Molecular Oncology, Poznań, Poland - Special thanks to Maciej Wiznerowicz MD, PhD and Jan Lubiński MD PhD, Tomasz Czernicki MD, PhD and Andrzej Marchel MD, PhD from Central Clinical Hospital in Warsaw, Pawel Jarmużek MD, PhD, Jakub Stawicki MD and Piotr Makarewicz MD from Karol Marcinkowski Regional Clinical Hospital in Zielona Góra; and Wojciech Szopa MD, PhD and Wojciech Kaspera MD, PhD from Regional Clinical Hospital Sosnowiec in Poland.
- St. Joseph's Hospital and Medical Center, Phoenix, AZ - Special thanks to Jennifer Eschbacher, MD from the Department of Neuropathology, Catherine Seiler, PhD, Rosy Singh and Beth Hermes from the Biobank Core Facility, and Victor Sisneros, RT(R)(CT), CPSA.
- University of Calgary, Alberta, Canada - Special thanks to Oliver Bathe, MD, FRCS(C) from the Departments of Surgery/Oncology, Marina Salluzzi, PhD and Nicole Blenkin from the Department of Radiology, Calgary Image Processing and Analysis Centre (CIPAC), and Jennifer Koziak from the Department of Surgery.<coming soon>
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