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Summary

This collection contains imaging, radiation therapy, and clinical data from 627 head and neck squamous cell carcinoma (HNSCC) patients at MD Anderson Cancer Center.  The data were collected Researchers at MDACC analyzed these patients' data as part of two separate research projects which had overlapping patient cohorts.  70 of the patients were selected for inclusion in both projects. This collection provides access to all data for the full set of patients involved in both projects, but download .  Download options for the individual studies are also available as described available by following the links in each project description below.

The first project screened 2840 consecutive patients with HNSCC treated with curative-intent RT at MD Anderson Cancer Center from 2003 to 2013. Patients with whole-body PET-CT or abdominal CT scans both before and after RT (n=215) were selected for the cohort.  De-identified diagnostic imaging, radiation treatment planning, and follow up imaging are provided. Using cross sectional imaging, total body skeletal muscle and adipose content were calculated before and after treatment.  All imaging data are subject- and date-matched to clinical data from each patient, including demographics, risk factors, grade, stage, recurrence, and survival. Open access to these data allows for inter-institutional comparisons of complete RT details in non-randomized patient populations, allowing for a more granular understanding of three dimensional factors that influence treatment effectiveness and toxicity sparing.  More information about this study and links to download the corresponding patient subset of this collection including clinical data can be found in the "Data from Head and Neck Cancer CT Atlas" dataset.

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