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T2w MRI at 56 days post implant demonstrated a heterogenous tumor with an apparent central hemorrhage and the implant appears to have a defined capsule.  On day 98 (post-implant) the tumor increased in size (618%) with very similar imaging characteristics as displayed on day 56.

In contrast, the regrowth following surgical resection of the primary xenograft (105 days post resection) is homogenous, but also appears to have a well-defined capsule.

PET/CT Characterization of the primary tumor:  Baseline PET (SOP attached) were performed when tumor reached an approximate 200 mm³.   Average SUVmax Average SUVbw_max values (n=5) were calculated; [¹⁸F]FDG: 1.8 ± 0.2 and [¹⁸F]FLT: 2.8 ± 0.7.

The imaging characteristics of this model, which is available from the National Cancer Institute Patient-Derived Models Repository (https://pdmr.cancer.gov/), is highly favorable for preclinical research studies when used in conjunction with non-contrast T2 weighted MRI.