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  • Breast Multiparametric MRI for prediction of NAC Response Challenge (BMMR2 Challenge)

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  1. Single-breast ipsilateral cropped DCE images
    1. As this was done primarily for computational efficiency, low matrix-sized images (<384 voxels per row) were stored and processed without cropping
  2. Enhancement maps
    1. PEearly: Enhancement at effective post-contrast time 120-150 sec
    2. PElate: Enhancement at effective post-contrast time ~450 sec
    3. SER: Signal enhancement ratio    SER =  PEearly / PElate
      Note: SER values were scaled by 1000 for integer storage. DICOM software utilizing the rescale slope and intercept fields [ DICOM fields (0028, 1052-1054)] should return the original SER values in the range from 0.0 – 3.0.
    4. All maps were stored as DICOM MRI objects
  3. Functional Tumor Volume (FTV) analysis mask
    1. Segmentation storing FTV masking. Encodes:
      1. Pre-contrast background threshold
      2. Minimum PE threshold (70% nom.)
      3. Manually defined rectangular volume of interest (VOI) for enhancing tumor analysis
      4. Manually defined “OMIT” regions used to exclude non-tumor enhancing regions that encroached on the rectangular VOI
    2. Stored as DICOM SEG object
    3. See this document for further information: Analysis Mask Files Descriptionmask files description

These DCE derived series can be identified either by Series Description (0008,103e) or by Series Number (0020,0011). See Table 1 for series identification details.

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  1. For studies with test/retest DWI scans the prefixes on the series descriptions for the derived DWI objects will be “ACRIN-6698: TrT0:” and “ACRIN-6698: TrT1” for the 1st and 2nd scans respectively.
  2. FTV (functional tumor volume) Analysis Masks are bit-encoded segmentations encoding all masking steps in the I‑SPY 2 primary FTV analysis. See document Analysis Mask Files Descriptionmask files description for a full description of these objects.
  3. DCE images with less than 384 voxels/row were not cropped for the FTV analysis. For these studies the derived DCE objects are all full bilateral images.

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  • ACRIN 6698 MRI protocol parameter specifications

  • DCE analysis mask description. This file provides usage information for the functional tumor volume analysis masks provided as part of the DCE derived objects package
    Analysis Mask Files Descriptionmask files description

  • DICOM Dictionary for UCSF private attributes
    [[[XXX need to finalize ]]]

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