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  • MRQy quality measures for TCIA MRI datasets (MRQy-Quality-Measures)

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Summary

Excerpt

These quality assessment results measures were generated for for 

  1. T1-weighted post-contrast axial MRI sequences from 133 TCGA-GBM
subjects for whom a
  1. subjects 
  2. T1-weighted post-contrast axial MRI sequences from 46 CPTAC-GBM subjects  
  3. Both T1- and T2-weighted axial MRI sequences from 54 TCGA-CESC subjects

All MRI scans for each cohort POST sequence in the axial plane was available, resulting in a cohort of n=133 T1-POST MRI scans accrued from 7 different sites. All 133 T1-POST studies were downloaded as DICOM files from TCIA and then processed via MRQy to compute quality measures for (a) interrogating the presence of site- or equipment-specific variations within a cohort, and (b) quantifying the impact of MRI artifacts to determine what pre-analytical corrections are needed. The MRQy output can be easily interrogated via the associated HTML5 based front-end, allowing for real-time filtering and visualization. MRQy is available for download at: http://github.com/ccipd/MRQy.  Links Manifest files to download the DICOM images these results were derived from are available on the Detailed Description page.

Acknowledgements

Research reported in this publication was supported by:

  • National Cancer Institute of the National Institutes of Health under award numbers 1U24CA199374-01, R01CA202752-01A1, R01CA208236-01A1, R01 CA216579-01A1, R01 CA220581-01A1, 1U01 CA239055-01, 1F31CA216935-01A1, NCI 1U01CA248226-01
  • National Institute for Biomedical Imaging and Bioengineering (1R43EB028736-01)
  • National Center for Research Resources under award number 1 C06 RR12463-01
  • VA Merit Review Award IBX004121A from the United States Department of Veterans Affairs Biomedical Laboratory Research and Development Service
  • The DoD Breast Cancer Research Program Breakthrough Level 1 Award (W81XWH-19-1-0668)
  • The DOD Prostate Cancer Idea Development Award (W81XWH-15-1-0558)
  • The DOD Lung Cancer Investigator-Initiated Translational Research Award (W81XWH-18-1-0440)
  • The DOD Peer Reviewed Cancer Research Program (W81XWH-16-1-0329, W81XWH-18-1-0404)
  • Dana Foundation David Mahoney Neuroimaging Program
  • The V Foundation Translational Research Award
  • The Ohio Third Frontier Technology Validation Fund
  • The Wallace H. Coulter Foundation Program in the Department of Biomedical Engineering
  • The Clinical and Translational Science Award Program (CTSA) at Case Western Reserve University

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