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The goal of the BMMR2 challenge was to identify image-based markers derived from DW-MRI, alone or in combination with DCE-MRI, with improved performance over whole-tumor mean ADC for predicting pCR following neoadjuvant chemotherapy (NAC) for invasive breast cancer. The challenge was being run by the Breast Imaging Research Program of UCSF through the NCI Quantitative Imaging Network (QIN). The challenge opened on June 1, 2021 and closed on December 1, 2021.
Data for the challenge consisted of a subset of the TCIA breast MRI collection from the American College of Radiology Imaging Network (ACRIN) trial 6698. 573 breast MRI studies from 191 subjects undergoing NAC for invasive breast cancer will be were provided, with the patient the patient cohort split 60%/40% into training and test groups. pCR pCR outcome data will be was provided for the training set. A brief description of the data set is provided below. For more information on the ACRIN 6698 collection see the TCIA collection description at at ACRIN 6698/I-SPY2 Breast DWI (ACRIN 6698). The challenge was hosted by MedICI Challenges.
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MRI studies performed during the course of NAC at three of the standard I-SPY 2 imaging time points will be were available for the challenge:
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Information on the ACRIN 6698 data collection: ACRIN 6698/I-SPY2 Breast DWI (ACRIN-6698)
Information on I-SPY 2 TRIAL: I-SPY 2 TRIAL
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