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Summary

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delay 5 location https://www.cancerimagingarchive.net/collection/qin-breast-dce-mri/

This collection of breast dynamic contrast-enhanced (DCE) MRI data contains images from a longitudinal study to assess breast cancer response to neoadjuvant chemotherapy. Images were acquired at four time points: prior to the start of treatment (Visit 1, V1), after the first cycle of treatment (Visit 2, V2), at midpoint of treatment course (Visit 3, V3), and after completion of treatment (prior to surgery) (Visit 4, V4). The value of this collection is to provide clinical imaging data for the development and validation of quantitative imaging methods for assessment of breast cancer response to treatment. Data is provided by Oregon Health & Science University, PI Dr. Wei Huang.

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A total of 20 data sets from this collection have been used for a multi-QIN center challenge, in which each participating site performed pharmacokinetic analysis of the breast DCE-MRI data using software tools/algorithms available to them. The shared data sets are from the V1 and V2 studies of 10 patients (BreastChemo 1, 5, 6, 8, 10, 12, 13, 14, 15, and 16) – 3 pathologic complete responders (pCRs) and 7 non-pCRs.  The goal of the challenge was to evaluate variations in DCE-MRI assessment of breast cancer response to neoadjuvant chemotherapy caused by differences in software tools/algorithms only. 

If your use of this collection results in a publication, we would appreciate if you cite the appropriate references and acknowledge the award that supported collection and sharing of these data sets (U01 CA154602, PI Wei Huang).  Please see the published paper for details of the challenge.

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title Reference
Huang W, Li X, Chen Y, Li X, Chang MC, Oborski MJ, Malyarenko DI, Muzi M, Jajamovich GH, Fedorov A, Tudorica A, Gupta SN, Laymon CM, Marro KI, Dyvorne HA, Miller JV, Barbodiak DP, Chenevert TL, Yankeelov TE, Mountz JM, Kinahan PE, Kikinis R, Taouli B, Fennessy F, Kalpathy-Cramer J.  Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge.  Trans Oncol 2014;7:153-166. PubMed PMID: 24772219; PubMed Central PMCID: PMC3998693. (link)

About the NCI QIN

The mission of the QIN is to improve the role of quantitative imaging for clinical decision making in oncology by developing and validating data acquisition, analysis methods, and tools to tailor treatment for individual patients and predict or monitor the response to drug or radiation therapy. More information is available on the Quantitative Imaging Network Collections page. Interested investigators can apply to the QIN at: Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01) PAR-11-150. 

 

Localtab Group

Click the Versions tab for more info about data releases. Localtab active true title Data Access Data Access Choosing the Download option will provide you with a file to launch the TCIA Download Manager to download the entire collection. If you want to browse or filter the data to select only specific scans/studies please use the Search By Collection option. Data Type Download all or Query/Filter License Images (DICOM + NIFTI, 15.8GB) Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/qin-dce-mri-challenge_DCM_NIFTI.tcia?version=1&modificationDate=1534786993310&api=v2 Tcia button generator label Search url https://nbia.cancerimagingarchive.net/nbia-search/?CollectionCriteria=QIN%20Breast%20DCE-MRI (Download requires the NBIA Data Retriever) Tcia cc by 3 Images (20 files, modality KO, datatype Matlab + DICOM, 49 8. 5 GB 4GB) Image Removed Image Removed Matlab (JNLP) Image Removed DICOM + NIFTI (JNLP) Image Removed Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/qin-dce-mri-challenge_Matlab.jnlp?version=1&modificationDate=1416273279384&api=v2 Tcia button generator label Search url https://nbia.cancerimagingarchive.net/nbia-search/?saved-cart=nbia-9971689371318441 Tcia cc by 3 Pathological Response (XLS, 10 kB) Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/QIN-Breast-DCE-MRI_Response.xlsx?version=1&modificationDate=1467916192583&api=v2 Tcia cc by 3 Population-averaged AIF timecourse (XLSX, 24 kB) Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/QIN%2BBreast%2BDCE-MRI_AIF.xlsx?version=1&modificationDate=1555605930976&api=v2 Tcia cc by 3 Nci_crdc additional resources Imaging Data Commons (IDC) (Imaging Data)

Localtab
title Detailed Description
Detailed Description Collection Statistics Updated 07/02/2014 Modalities MR, KO Number of Patients Participants 10 Number of Studies 20 Number of Series 672 Number of Images 76,328 Image Size (GB) 49.5   Matlab and NIFTI Data As part of the multi-QIN center challenge additional files were created to help facilitate participation.  There are essentially two versions of the data available.  These files are available inside of TCIA alongside the DICOM data, and are most easily accessed using one of the Shared Lists mentioned above. Matlab - contains all relevant information including the raw image data, DICOM header info, and all other relevant parameters necessary to analyze the data for the challenge.  There is no need to download the raw DICOM data if you prefer this format. DICOM + NIFTI - useful if you'd prefer to work in 3D Slicer or some other application which supports DICOM and NIFTI formats Clinical Data Pathologic response status for the patients: Complete response QIN-Breast-DCE-MRI-BC05 QIN-Breast-DCE-MRI-BC06 QIN-Breast-DCE-MRI-BC15 Non-complete response QIN-Breast-DCE-MRI-BC01 QIN-Breast-DCE-MRI-BC08 QIN-Breast-DCE-MRI-BC10 QIN-Breast-DCE-MRI-BC12 QIN-Breast-DCE-MRI-BC13 QIN-Breast-DCE-MRI-BC14 QIN-Breast-DCE-MRI-BC16 For inquiries on inquiries on AIF (Arterial Input Function) used for pharmacokinetic analysis of the breast DCE-MRI data, users are encouraged to contact help@cancerimagingarchive.net who can direct you to Dr. Huang.   Other Publications Using This Data Huang W, Li X, Chen Y, Li X, Chang MC, Oborski MJ, Malyarenko DI, Muzi M, Jajamovich GH, Fedorov A, Tudorica A, Gupta SN, Laymon CM, Marro KI, Dyvorne HA, Miller JV, Barbodiak DP, Chenevert TL, Yankeelov TE, Mountz JM, Kinahan PE, Kikinis R, Taouli B, Fennessy F, Kalpathy-Cramer J.  Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge.  Trans Oncol 2014;7:153-166. PubMed PMID: 24772219; PubMed Central PMCID: PMC3998693. (link) TCIA maintains a list of publications which leverage our data. At this time we are not aware of any publications based on this data. If you have a publication you'd like to add please contact the TCIA Helpdesk.
Localtab
title Citations & Data Usage Policy
start here: QIN+Breast+DCE-MRI_AIF.xlsx

Localtab
title Citations & Data Usage Policy
Citations & Data Usage Policy  Tcia limited license policy Info title Data Citation Huang, W., Tudorica, A., Chui, S., Kemmer, K., Naik, A., Troxell, M., Oh, K., Roy, N., Afzal, A., & Holtorf, M. (2014). Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge (QIN Breast DCE-MRI) (Version 2) [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/k9/tcia.2014.a2n1ixox Info title Publication Citation Huang, W., Li, X., Chen, Y., Li, X., Chang, M.-C., Oborski, M. J., Malyarenko, D. I., Muzi, M., Jajamovich, G. H., Fedorov, A., Tudorica, A., Gupta, S. N., Laymon, C. M., Marro, K. I., Dyvorne, H. A., Miller, J. V., Barbodiak, D. P., Chenevert, T. L., Yankeelov, T. E., Mountz J.M., Kinahan P.E., Kikinis R., Taouli B., Fennessy F., & Kalpathy-Cramer, J. (2014). Variations of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Evaluation of Breast Cancer Therapy Response: A Multicenter Data Analysis Challenge. In Translational Oncology (Vol. 7, Issue 1, pp. 153–166). Elsevier BV. https://doi.org/10.1593/tlo.13838 PMCID: PMC3998693 Citations & Data Usage Policy  This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License.  See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net. Please be sure to include the following citations in your work if you use this data set: Info title QIN-Breast DCE-MRI Citation The Cancer Imaging Archive Team. Data From QIN-Breast DCE-MRI. doi:10.7937/K9/TCIA.2015.PNVT2A29 Info title TCIA Citation Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F.  (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, . In Journal of Digital Imaging , Volume (Vol. 26, Number Issue 6, December, 2013, pp 1045-1057. (paper) Info title Publication Citation Huang W, Li X, Chen Y, Li X, Chang MC, Oborski MJ, Malyarenko DI, Muzi M, Jajamovich GH, Fedorov A, Tudorica A, Gupta SN, Laymon CM, Marro KI, Dyvorne HA, Miller JV, Barbodiak DP, Chenevert TL, Yankeelov TE, Mountz JM, Kinahan PE, Kikinis R, Taouli B, Fennessy F, Kalpathy-Cramer J.  Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge.  Trans Oncol 2014;7:153-166. PubMed PMID: 24772219; PubMed Central PMCID: PMC3998693. (link)1045–1057). Springer Science and Business Media LLC. https://doi.org/10.1007/s10278-013-9622-7 PMCID: PMC3824915 Other Publications Using This Data TCIA maintains a list of publications which leverage our data. At this time we are not aware of any publications based on this data. If you have a publication manuscript you'd like to add, please contact the TCIA's Helpdesk.

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Localtab
title Versions
Version 1 2 (Current): Updated 2014 2019/ 07 04/ 02 18 Data Type Download all or Query/Filter Images (DICOM + NIFTI, 49 15. 5GB)	Image Removed Image Removed
Matlab (JNLP)	Image Removed
DICOM + NIFTI (JNLP)

8GB)	Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/qin-dce-mri-challenge_DCM_NIFTI.tcia?version=1&modificationDate=1534786993310&api=v2 Tcia button generator label Search url https://nbia.cancerimagingarchive.net/nbia-search/?CollectionCriteria=QIN%20Breast%20DCE-MRI    (Download requires the NBIA Data Retriever)
Images (Matlab, 8.4GB)	Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/qin-dce-mri-challenge_Matlab.jnlp?version=1&modificationDate=1416273279384&api=v2 Tcia button generator label Search url https://nbia.cancerimagingarchive.net/nbia-search/?saved-cart=nbia-9971689371318441 (Download requires the NBIA Data Retriever)
Population-averaged AIF timecourse (XLSX)	Tcia button generator url https://wiki.cancerimagingarchive.net/download/attachments/18514286/QIN%2BBreast%2BDCE-MRI_AIF.xlsx?version=1&modificationDate=1555605930976&api=v2