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Summary

Redirect
delay5
locationhttps://www.cancerimagingarchive.net/collection/head-neck-cetuximab/
This collection combines advanced molecular imaging treatment response assessment through pre- and post-treatment FDG PET/CT scans with therapy of advanced head and neck cancer, including chemo-radiation therapy with and without addition of an EGFR inhibitor
molecular inhibitor molecular targeted agent (Cetuximab). 

The Head-Neck Cetuximab collection consists of a subset of image data from RTOG 0522/ACRIN 4500, which was randomized phase III Trial of Radiation Therapy and Chemotherapy for stage III and IV Head and Neck carcinomas. The RTOG 0522 /ACRIN 4500 protocols were activated in November 2005 and successfully completed accrual of 945 patients in 2009. As part of the RTOG 0522 trial, CT, Structures, RT Doses, RT Plans were collected by RTOG, and institutions had the option to join the RTOG 0522/ACRIN 4500 imaging studya related quantitative PET (PET/CT) imaging study with ACRIN. The post-treatment FDG PET/CT scan was performed 8-9 weeks after completion of treatment before any nodal dissection.  For this reason the data was provided through two independent channels:

  • RTOG 0522: CT, Structures, RT Doses, RT Plans sent to ITC
  • ACRIN 4500: Quantitative PET (PET/CT) sent to ACRIN

For more information about the original aims of this trial please see : httphttps://meetingclinicaltrials.ascopubs.orggov/cgict2/contentshow/abstract/29/15_suppl/5500.

 

 

results/NCT00265941?term=rtog0522 and this PDF.

Localtab Group



Localtab
activetrue
titleData Access

Data Access

Choosing the Download option will provide you with a file to launch the TCIA Download Manager to download the entire collection. If you want to browse or filter the data to select only specific scans/studies please use the Search By Collection option.

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Data TypeDownload all or Query/Filter
Images (DICOM, 1.16GB)Image Removed Image Removed
Spreadsheet (XLS)
License
Images and Radiation Therapy Structures (48.8GB)


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urlhttps://wiki.cancerimagingarchive.net/download/attachments/6884551/TCIA_Head-Neck_Cetuximab_06-22-2015.tcia?version=1&modificationDate=1534787422712&api=v2



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labelSearch
urlhttps://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=Head-Neck%20Cetuximab



(Download requires the NBIA Data Retriever)

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DICOM Metadata Digest (CSV, 277 kB)


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urlhttps://wiki.cancerimagingarchive.net/download/attachments/6884551/HeadNeckCetuximab_MetaData.csv?version=2&modificationDate=1495560309184&api=v2



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Localtab
titleDetailed Description

Detailed Description


Collection Statistics

Updated 11/09/2011


Modalities

MR (with some PET/CT)

PT, CT, RTSTRUCT, RTDOSE, RTPLAN

Number of

Patients

Participants

88

111

Number of Studies

148

368

Number of Series

429

1,682

Number of Images

105

202,

050

574

Image Size (GB)
1
48.
16

 

Metadata

8


Supporting Documentation and metadata

Please note that 10 cases in this collection do not contain RT data.  Eight cases whose RT QA scores that were not "Per Protocol" or "Variation Acceptable" were excluded:  96, 133, 141, 143, 154, 182, 475, 478.  Also, subject 243 was ineligible and subject 260 expired prior to follow-upThis collection includes a spreadsheet (updated 7/16/11) with BIRADS MRI features from the imaging report and denoted key image slice with the approximate X-Y center position if a mass was found. Key clinical features and abstracts of the pathology report including ER, PR and HER2 results and Oncotype score are included when available.




Localtab
titleCitations & Data Usage Policy

Citations & Data Usage Policy 

This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License.  See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net. Please be sure to acknowledge both this data set and TCIA in publications by including the following citations in your work:

Tcia limited license policy


Info
titleData Citation

Bosch, W. R., Straube, W. L., Matthews, J. W., & Purdy, J. A. (2015). Head-Neck Cetuximab [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2015.7AKGJUPZ


Info
titlePublication Citation

Ang, K. K., Zhang, Q., Rosenthal, D. I., Nguyen-Tan, P. F., Sherman, E. J., Weber, R. S., Galvin, J. M., Bonner, J. A., Harris, J., El-Naggar, A. K., Gillison, M. L., Jordan, R. C., Konski, A. A., Thorstad, W. L., Trotti, A., Beitler, J. J., Garden, A. S., Spanos, W. J., Yom, S. S., & Axelrod, R. S. (2014). Randomized Phase III Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Stage III to IV Head and Neck Carcinoma: RTOG 0522. In Journal of Clinical Oncology (Vol. 32, Issue 27, pp. 2940–2950). American Society of Clinical Oncology (ASCO). https://doi.org/10.1200/jco.2013.53.5633

Info
titleCT Colonography Citation

The Cancer Imaging Archive Team. Data From BREAST-DIAGNOSIS. doi:10.7937/K9/TCIA.2015.SDNRQXXR


Info
titleTCIA Citation

Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F.  (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, . In Journal of Digital Imaging , Volume (Vol. 26, Number Issue 6, December, 2013, pp 1045-1057. (paper)1045–1057). Springer Science and Business Media LLC. https://doi.org/10.1007/s10278-013-9622-7 PMCID: PMC3824915

Other Publications Using This Data

  • At this time we are not aware of any manuscripts based on this data.

TCIA maintains a list of publications which leverage our data. If you have a manuscript you'd like to add please contact

the

TCIA

Helpdesk.
Localtab
titleVersions

Version 1 (Current): Updated 2011/11/09

Data TypeDownload all or Query/Filter
Images (DICOM, 1.16GB)Image Removed Image Removed
Spreadsheet (XLS)Image Removed

 

Data Access

Imaging Data

Info

You can view and download these images on TCIA by clicking Image Removed and selecting the Head-Neck Cetuximab collection.

Collection Statistics

Updated 11/14/2013

Modalities

PT, CT, RTSTRUCT, RTDOSE, RTPLAN

Number of Patients

111

Number of Studies

368

Number of Series

1,682

Number of Images

202,574

Image Size (GB)48.8

If you are unsure how to download this Collection please view our quick guide on Searching by Collection or refer to our The Cancer Imaging Archive User's Guide for more detailed instructions on using the site.

Shared Lists

  • None available at this time

Note: See Section 3.7 of TCIA User Guide for help with Shared Lists.

Supporting Documentation and metadata

Please note that 10 cases in this collection do not contain RT data.  Eight cases whose RT QA scores that were not "Per Protocol" or "Variation Acceptable" were excluded:  96, 133, 141, 143, 154, 182, 475, 478.  Also, subject 243 was ineligible and subject 260 expired prior to follow-up.

 

's Helpdesk.

  1. AlZu'bi, Shadi et al. "Transferable Hmm Probability Matrices in Multi‐Orientation Geometric Medical Volumes Segmentation." Concurrency and Computation: Practice and Experience, 2019, p. e5214, doi:10.1002/cpe.5214.
  2. Edwards, Samuel et al. "Automated 3-D Tissue Segmentation Via Clustering." Journal of Biomedical Engineering and Medical Imaging, vol. 5, no. 2, 2018, p. 08, doi: 10.14738/jbemi.52.4204.
  3. Gruselius, H. (2018).  Generative models and feature extraction on patient images and structure data in radiation therapy. Retrieved from  http://kth.diva-portal.org/smash/record.jsf?pid=diva2%3A1215620&dswid=2429

  4. Ryalat MH, Laycock S, Fisher M, editors.  Automatic Removal of Mechanical Fixations from CT Imagery with Particle Swarm Optimisation. International Conference on Bioinformatics and Biomedical Engineering; 2017: Springer. DOI:  10.1007/978-3-319-56148-6_37
  5. Sando, Yusuke et al. "Real-Time Interactive Holographic 3d Display with a 360 Degrees Horizontal Viewing Zone." Appl Opt, vol. 58, no. 34, 2019, pp. G1-G5, doi:10.1364/AO.58.0000G1.
  6. Scarpelli, M. et al. "Optimal Transformations Leading to Normal Distributions of Positron Emission Tomography Standardized Uptake Values." Phys Med Biol, vol. 63, no. 3, 2018, p. 035021, doi:10.1088/1361-6560/aaa175
  7. Sinha, A. et al. "The Deformable Most-Likely-Point Paradigm." Med Image Anal, vol. 55, 2019, pp. 148-164, doi:10.1016/j.media.2019.04.013.
  8. Sinha, A. et al. "Recovering Physiological Changes in Nasal Anatomy with Confidence Estimates." First International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, UNSURE 2019, edited by Hayit Greenspan et al., Springer, 2019. doi:10.1007/978-3-030-32689-0_12.
  9. Tang, Hao et al. "Clinically Applicable Deep Learning Framework for Organs at Risk Delineation in Ct Images." Nature Machine Intelligence, vol. 1, no. 10, 2019, pp. 480-491, doi:10.1038/s42256-019-0099-z.
  10. Teske, Hendrik et al. "Handling Images of Patient Postures in Arms up and Arms Down Position Using a Biomechanical Skeleton Model." Current Directions in Biomedical Engineering, vol. 3, no. 2, 2017, pp. 469-472, doi:10.1515/cdbme-2017-0099.
  11. Wong, Jordan et al. "Comparing Deep Learning-Based Auto-Segmentation of Organs at Risk and Clinical Target Volumes to Expert Inter-Observer Variability in Radiotherapy Planning." Radiother Oncol, vol. 144, 2019, pp. 152-158, doi:10.1016/j.radonc.2019.10.019.
  12. Zhu, Wentao. "Deep Learning for Automated Medical Image Analysis." Computer Science, vol. Ph.D, University of California, Irvine, 15 March 2019 2019. general editor, Xiaohui Xie et al., https://arxiv.org/pdf/1903.04711.pdf.
  13. Zhu, Wentao et al. "Anatomynet: Deep Learning for Fast and Fully Automated Whole‐Volume Segmentation of Head and Neck Anatomy." Medical Physics, vol. 46, no. 2, 2018, pp. 576-589, doi:https://doi.org/10.1002/mp.13300





Localtab
titleVersions

Version 1 (Current): Updated 2013/11/14


Data TypeDownload all or Query/Filter
Images (48.8GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/6884551/TCIA_Head-Neck_Cetuximab_06-22-2015.tcia?version=1&modificationDate=1534787422712&api=v2



Tcia button generator
labelSearch
urlhttps://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=Head-Neck%20Cetuximab



(Requires the NBIA Data Retriever .)

DICOM Metadata Digest (CSV)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/6884551/HeadNeckCetuximab_MetaData.csv?version=2&modificationDate=1495560309184&api=v2