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Summary
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This collection consists of DICOM images and DICOM Segmentation Objects (DSOs) for 198 (there are only 196) 197 patients with Colorectal Liver Metastases (CRLM). The collection consists of a large, single-institution consecutive series of patients that underwent resection of CRLM and matched preoperative computed tomography (CT) scans for quantitative image analysis. Inclusion criteria were (a) pathologically confirmed resected CRLM, (b) available data from pathologic analysis of the underlying non-tumoral liver parenchyma and hepatic tumor, (c) available preoperative conventional portal venous contrast-enhanced multi-detector computed tomography (MDCT) performed within 6 weeks of hepatic resection. Patients with 90-day mortality or that had less than 24 months of follow-up were excluded. Additionally, because pathologic and radiographic alterations of the non-tumoral liver parenchyma caused by hepatic artery infusion (HAI) of chemotherapy are not well described, any patient who received preoperative HAI was excluded. Finally, to obtain the most accurate future liver remnant (FLR), patients who underwent either local tumor ablation, more than 3 wedge resections, or had no visible tumor on preoperative imaging were excluded. The corresponding clinical dataset provides the variables collected including demographic, pathologic and survival data along with a data dictionary. This dataset is further described in the following publication: Simpson AL, Doussot A, Creasy JM, et al. Computed Tomography Image Texture: A Noninvasive Prognostic Marker of Hepatic Recurrence After Hepatectomy for Metastatic Colorectal Cancer. Ann Surg Oncol. 2017;24(9):2482-2490. doi:10.1245/s10434-017-5896-1 The CT images were extracted from PACS and de-identified via institutional approved & and a HIPAA compliant method. The regions of interest (e.g., tumor, liver, vessels) were delineated from the scan using Scout softwareliver, tumors, and vessels were semi-automatically segmented and a 3D model was generated using Scout Liver (Pathfinder Technologies Inc., TN, USA). Post-operative imaging and/or the resection margin width from pathology analysis were used to determine the transection lines needed to generate the segmentation of the liver remnant after surgery. Our informatics team converted the native MHD segmentation files into a readable and TCIA compliant DSO format. Dataset: (There are no subfolders as described when using NBIA data retriever) The subfolders inside a subject folder are organized as follows: DICOM-SEG format using the open-source dcmqi software. The segments in a given DICOM Segmentation Object (DSO) can be consistently identified using the Segment Label header, which follows the naming scheme described below. The SCT codes used to categorize the segments in the Segmented Property Type Code Sequence header may be updated in future releases to comply with best practices. Dataset: The dataset inside a subject folder is organized as follows:
The DSOs The MHD and DSO segmentations are verified for all cases. Case "CRLM-CT-1074" was scanned with the subject in a prone (laying on stomach) position, so the images are in a different orientation than usual. |
Acknowledgements
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This study was funded in part through the NIH/NCI Cancer Center Support GrantP30 Grant P30 CA008748 and NIH supported grant R01CA233888.
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