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  • The Cancer Genome Atlas Breast Invasive Carcinoma Collection (TCGA-BRCA)

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Excerpt

The Cancer Genome Atlas-Brest Breast Cancer (TCGA-BRCA) data collection is part of a larger effort to enhance the TCGA data set with characterized radiological images. The Cancer Imaging Program (CIP), with the cooperation of several of the TCGA tissue-contributing institutions, are working to archive a large portion of the radiological images of the genetically-analyzed breast cancer BRCA cases.

Clinical, genetic, and pathological data resides in the TCGA data portal, while the radiological data is stored on The Cancer Imaging Archive (TCIA). The data utilizes the same TCGA patient identifiers in both repositories, allowing researchers to explore the correlations between tissue genotype and radiological phenotype. This collection within TCIA is related to the BRCA disease type within TCGA.

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The CIP has begun multiple projects to collaborate with the academic community to encourage cross disciplinary research, which utilizes the data provided in these resources. Much more More can be learned about this effort on the TCGA Breast Phenotype Research Group page.

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Info

You can view and download these images on TCIA by logging in and selecting the TCGA-BRCA collection. A full listing of the available imaging studies/series for each patient can be found in this spreadsheet: TCGA-BRCA.XLSX.

Collection Statistics

Updated 12/11/2013

Modalities

magnetic resonance (MR), mammography (MG)

Number of Patients

122

Number of Studies

144

Number of Series

1,662

Number of Images

153,447

If you are unsure how to download this collection, please view Searching by Collection or refer to our to TCIA's User's Guide for more detailed instructions on using the site.

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The TCGA data portal has extensive clinical and genomic data, which can be matched to the patient identifiers of the images here in TCIA. 

Explanations of the clinical data can be found on the Biospecimen Core Resource Clinical Data Forms linked below:

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  • Mayo Clinic, Rochester, MN - Special thanks to Wilma Lingle, MD and Bradley J. Erickson, MD, PhDPh.D. from the Department of Radiology, Mayo Medical School.
  • University of Pittsburgh/UPMC, Pittsburgh, PA - Special thanks to  Margarita L Zuley, MD and Rose Jarosz.
  • Roswell Park, Buffalo, NY - Special thanks to Ermelinda Bonaccio, MD and Joe Filippini from the Department of Diagnostic Radiology.

  • University of Miami, Miller School of Medicine, Miami, FL - Special thanks to Jose M. Net, MD and Len Levi.

  • Memorial Sloan-Kettering Cancer Center/MSKCC, New York, NY - Special thanks to Elizabeth A Morris MD, Gloria Guman Figler, and Pierre Elnajjar.

  • University of North Carolina, Chapel Hill, NC - Special thanks to J. Keith Smith, MD, PHDPh.D. and Shanah Kirk from the Department of Radiology.

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