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The RIDER Lung CT collection was constructed as part of a study to evaluate the variability of tumor unidimensional, bidimensional, and volumetric measurements on same-day repeat computed tomographic (CT) scans in patients with non–small cell lung cancer. |
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| location | https://www.cancerimagingarchive.net/collection/rider-breast-mri/ |
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Ideally a patient’s response to neoadjuvant chemotherapy could be observed noninvasively, in the first 2-3 weeks of treatment using an imaging to provide feedback related to the effectiveness of the chosen chemotherapy regimen. This capability would permit individuation of patient care by supporting the opportunity to tailor chemotherapy to a each patient’s response. Functional diffusion mapping (fDM), now called Parametric Response Mapping (PRM) has been proposed as an MRI imaging biomarker for quantifying early brain tumor response to therapy [1-3]. This approach quantifies local apparent diffusion coefficient (ADC) changes in tumors using a voxel-based analysis implemented by rigid registration of the patient’s head between interval exams. The RIDER Breast MRI data set extended this approach by demonstrating ADC changes in 3 of 5 primary breast cancer patients measured in response to onset of neoadjuvant chemotherapy from interval exams separated by only 8-11 days. |
This ISMRM 2009 poster demonstrates how each of the "coffee break" exams were used as an estimate of each patient's null hypothesis, i.e. distribution associated with no change, and thus supports the estimate of the nulls 97.5 percentile for subsequent estimation of early response to neoadjuvant chemotherapy on an individual patient basis
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About the RIDER project
The Reference Image Database to Evaluate Therapy Response (RIDER) is a targeted data collection used to generate an initial consensus on how to harmonize data collection and analysis for quantitative imaging methods applied to measure the response to drug or radiation therapy. The National Cancer Institute (NCI) has exercised a series of contracts with specific academic sites for collection of repeat "coffee break," longitudinal phantom, and patient data for a range of imaging modalities (currently computed tomography [CT] positron emission tomography [PET] CT, dynamic contrast-enhanced magnetic resonance imaging [DCE MRI], diffusion-weighted [DW] MRI) and organ sites (currently lung, breast, and neuro). The methods for data collection, analysis, and results are described in the new Combined RIDER White Paper Report (Sept 2008):
The long term goal is to provide a resource to permit harmonized methods for data collection and analysis across different commercial imaging platforms to support multi-site clinical trials, using imaging as a biomarker for therapy response. Thus, the database should permit an objective comparison of methods for data collection and analysis as a national and international resource as described in the first RIDER white paper report (2006):
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Choosing the Download option will provide you with a file to launch the TCIA Download Manager to download the entire collection. If you want to browse or filter the data to select only specific scans/studies please use the Search By Collection option.
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| url | https://wiki.cancerimagingarchive.net/download/attachments/22512757/doiJNLP-Fo0H1NtD.tcia?version=1&modificationDate=1534787017928&api=v2 |
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| url | https://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=RIDER%20Breast%20MRI |
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(Download requires the NBIA Data Retriever) | | | DICOM Metadata Digest (CSV, 7 kB) |
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| url | https://wiki.cancerimagingarchive.net/download/attachments/22512757/RIDERBreastMRI_MetaData.csv?version=1&modificationDate=1495728604329&api=v2 |
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Click the Versions tab for more info about data releases. | Nci_crdc additional resources |
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| Detailed Description
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Participants | 5 | Number of Studies | 10 | Number of Series | 40 | Number of Images |
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| title | Citations & Data Usage Policy |
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| Citations & Data Usage Policy |
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This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.
Please be sure to include the following citations in your work if you use this data set:
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| Info |
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| Meyer, C. R., Chenevert, T. L., Galbán, C. J., Johnson, T. D., Hamstra, D. A., Rehemtulla, A., & Ross, B. D. (2015). RIDER Breast MRI [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2015.H1SXNUXL |
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| title | RIDER Breast MRI Citation |
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| Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). |
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The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository |
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| Version 1 (Current): Updated 2011/11/08
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| url | https://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=RIDER%20Breast%20MRI |
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(Download requires the NBIA Data Retriever) | | DICOM Metadata Digest (CSV) |
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| url | https://wiki.cancerimagingarchive.net/download/attachments/22512757/RIDERBreastMRI_MetaData.csv?version=1&modificationDate=1495728604329&api=v2 |
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