Thursday evening the 17th at 7 pm there will be a 5 minute disruption in TCIA as the primary firewalls are updated to the latest in-version software. On Thursday the 24th, there be another 5-10 minute disruption as the primary firewalls are moved to new hardware.

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  1. Meyer JM, Perlewitz KS, Hayden JB, Doung Y-C, Hung AY, Vetto JT, Pommier RF, Mansoor A, Beckett BR, Tudorica A. Phase I trial of preoperative chemoradiation plus sorafenib for high-risk extremity soft tissue sarcomas with dynamic contrast-enhanced MRI correlates. Clinical Cancer Research. 2013;19(24):6902-11.

Collection:  REMBRANDT

Collection: RIDER Collections

  1. Barani R, Sumathi M. A New Adaptive-Weighted Fusion Rule for Wavelet based PET/CT Fusion. International Journal of Signal Processing, Image Processing and Pattern Recognition. 2016;9(11):271-82. DOI: 10.14257/ijsip.2016.9.11.25
  2. Aerts, H. J. W. L. et al. Defining a Radiomic Response Phenotype: A Pilot Study using targeted therapy in NSCLC. Sci. Rep.(2016) 6, 33860 (link)
  3. Oliveira B, O'Halloran M, Conceicao R, Glavin M, Jones E. Development of Clinically-Informed 3D Tumor Models for Microwave Imaging Applications. IEEE Antennas and Wireless Propagation Letters 2016;15:520-3. DOI: 10.1109/LAWP.2015.2456051

  4. Melouah A. Comparison of Automatic Seed Generation Methods for Breast Tumor Detection Using Region Growing Technique.  Computer Science and Its Applications: Springer; 2015. p. 119-28.
  5. Aerts HJ, Velazquez ER, Leijenaar RTH, Parmar C, et al. Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nature Communications, 2014. 5(4006). DOI:10.1038/ncomms5006 (link)
  6. Balagurunathan Y, Kumar V, Gu Y, Kim J, Wang H, Liu Y, Goldgof DB, Hall LO, Korn R, Zhao B. Test–Retest Reproducibility Analysis of Lung CT Image Features. Journal of digital imaging. 2014:1-19.
  7. Melouah, A. (2015). Comparison of Automatic Seed Generation Methods for Breast Tumor Detection Using Region Growing Technique. Computer Science and Its Applications, Springer: 119-128.
    Desseroit M-C, Visvikis D, Tixier F, Majdoub M, Perdrisot R, Guillevin R, Le Rest CC, Hatt M. Development of a nomogram combining clinical staging with 18F-FDG PET/CT image features in non-small-cell lung cancer stage I–III. European journal of nuclear medicine and molecular imaging. 2016:1-9. DOI: 10.1007/s00259-016-3325-5  


titleThese refer to the RIDER Collections data, created before submission to TCIA
  1. Meyer CR, Armato SG III, Fenimore CP, McLennan G, Bidaut LM, Barboriak DP, Gavrielides MA, Jackson EF, McNitt-Gray MF, Kinahan PE, Petrick N, Zhao B. Quantitative imaging to assess tumor response to therapy: Common themes of measurement, truth data and error sources. Translational Oncology 2: 198–210, 2009. (link)
  2. McNitt-Gray MF, Bidaut LM, Armato SG III, Meyer CR, Gavrielides MA, Fenimore CP, McLennan G, Petrick N, Zhao B, Reeves AP, Beichel R, Kim H-J, Kinnard L. CT assessment of response to therapy: Tumor volume change measurement, truth data and error.Translational Oncology2009. 2:216–222. (link)
  3. Kinahan PE, Doot RK, Wanner-Roybal M, Bidaut LM, Armato SG III, Meyer CR, McLennan G.PET/CT assessment of response to therapy: Tumor change measurement, truth data and error.Translational Oncology 2:223–230, 2009. (link)
  4. Jackson EF, Barboriak DP, Bidaut LM, Meyer CR. Magnetic resonance assessment of response to therapy: tumor change measurement, truth data and error sources.Translational Oncology 2009 Dec;2(4):211-5. PubMed PMID: 19956380; PubMed Central PMCID: PMC2781079. (link)
  5. Armato SG 3rd, Meyer CR, Mcnitt-Gray MF, McLennan G, Reeves AP, Croft BY, Clarke LP;RIDER Research Group. The Reference Image Database to Evaluate Response to therapy in lung cancer (RIDER) project: a resource for the development of change-analysis software.Clin Pharmacol Ther. 2008 Oct;84(4):448-56. PubMed PMID: 18754000. (link)

Collection: SPIE-AAPM Lung CT Challenge

  1. Park SY and Sargent D. Tumor propagation model using generalized hidden Markov model. Proc. SPIE 10133, Medical Imaging 2017: Image Processing, 101331G February 24, 2017); 10.1117/12.2254583
  2. Sargent D, Park S-Y. Semi-automatic 3D lung nodule segmentation in CT using dynamic programming. Proc. SPIE 10133, Medical Imaging 2017: Image Processing, 101332R (February 24, 2017) doi: 10.1117/12.2254575
  3. Nishio M, Nagashima C. Computer-aided Diagnosis for Lung Cancer: Usefulness of Nodule Heterogeneity. Academic Radiology. 2017;24(3):328-36. (link)


  1. Beig N, Patel J, Prasanna P, et al. Radiogenomic analysis of hypoxia pathway reveals computerized MRI descriptors predictive of overall survival in Glioblastoma. SPIE Medical Imaging; 2017; 10134:1-10. International Society for Optics and Photonics. doi:10.1117/12.2255694

  2. Lee, J.K., Wang, J., Sa, J.K., et al. Spatiotemporal genomic architecture informs precision oncology in glioblastoma. Nature Genetics.(2017) DOI: 10.1038/ng.3806

  3. Cui Y, Ren S, Tha KK, Wu J, Shirato H, Li R. Volume of high-risk intratumoral subregions at multi-parametric MR imaging predicts overall survival and complements molecular analysis of glioblastoma. European Radiology. 2017:1-10. (link)

  4. Kanas VG, Zacharaki EI, Thomas GA, Zinn PO, Megalooikonomou V, Colen RR. Learning MRI-based classification models for MGMT methylation status prediction in glioblastoma. Computer Methods and Programs in Biomedicine. 2017;140:249-57.(link)

  5. Czarnek N, Clark K, Peters KB, Mazurowski MA. Algorithmic three-dimensional analysis of tumor shape in MRI improves prognosis of survival in glioblastoma: a multi-institutional study. Journal of Neuro-Oncology. 2017:1-8. (link)

  6. Chaddad A, Desrosiers C, Toews M, editors. Radiomic analysis of multi-contrast brain MRI for the prediction of survival in patients with glioblastoma multiforme. Engineering in Medicine and Biology Society (EMBC), 2016 IEEE 38th Annual International Conference; 2016.

  7. Prasanna, P., Patel, J., Partovi, S. et al. Radiomic features from the peritumoral brain parenchyma on treatment-naïve multi-parametric MR imaging predict long versus short-term survival in glioblastoma multiforme: Preliminary findings.  Eur Radiol (2016) pp 1–10. DOI:10.1007/s00330-016-4637-3

  8. Mulvey M, Muhyadeen S,  Sinha U. Classification of Glioblastoma Multiforme Molecular Subtypes Using Three-Dimensional Multi-Modal MR Imaging Features. Med. Phys. 43, 3373 (2016); (link)

  9. Ren X, Cui Y, Gao H,  Li, R. Identifying High-Risk Tumor Volume Based On Multi-Region and Integrated Analysis of Multi-Parametric MR Images for Prognostication of Glioblastoma. Med. Phys. 43, 3751 (2016); (link)
  10. Dunn WD Jr,  Aerts HJWL, et al.  Assessing the Effects of Software Platforms on Volumetric Segmentation of Glioblastoma.   J   Neuroimaging Psychiatry Neurol 2016. 1(2): 64-72.
  11. Upadhaya T, Morvan Y, et al. Prognosis classification in glioblastoma multiforme using multimodal MRI derived heterogeneity textural features: impact of pre-processing choices. Proc. SPIE 9785, Medical Imaging 2016: Computer-Aided Diagnosis, 97850W (March 24, 2016); (link)
  12. Upadhaya T, Morvan Y, et al. Prognostic value of multimodal MRI tumor features in Glioblastoma multiforme using textural features analysis. In Biomedical Imaging (ISBI), 2015 IEEE 12th International Symposium on, pp. 50-54. IEEE, 2015.

  13. Upadhaya T, Morvan Y, et al. A framework for multimodal imaging-based prognostic model building: Preliminary study on multimodal MRI in Glioblastoma Multiforme. IRBM. 2015 Nov 30;36(6):345-50.

  14. Reza SM, Mays R, Iftekharuddin KM, editors. Multi-fractal detrended texture feature for brain tumor classification. SPIE Medical Imaging; 2015: International Society for Optics and Photonics.

  15. Nabizadeh N, Kubat M. Brain tumors detection and segmentation in MR images: Gabor wavelet vs. statistical features. Computers & Electrical Engineering. 2015.

  16. Natteshan N, Jothi JAA. Automatic Classification of Brain MRI Images Using SVM and Neural Network Classifiers.  Advances in Intelligent Informatics: Springer; 2015. p. 19-30. (link)

  17. Zhang J, Barboriak DP, Hobbs H, Mazurowski MA. A fully automatic extraction of magnetic resonance image features in Glioblastoma patients. Medical physics. 2014;41(4):042301.

  18. Wangaryattawanich P, Wang J, Thomas GA, Chaddad A, Zinn PO, Colen RR, editors. Survival analysis of pre-operative GBM patients by using quantitative image features. Control, Decision and Information Technologies (CoDIT), 2014 International Conference on; 2014: IEEE.

  19. Colen RR, Wang J, Singh SK, Gutman DA, Zinn PO. Glioblastoma: Imaging Genomic Mapping Reveals Sex-specific Oncogenic Associations of Cell Death. Radiology. 2014.

  20. Colen RR, Vangel M, Wang J, Gutman DA, Hwang SN, Wintermark M, Rajan J, Jilwan-Nicola M, Chen JY, Raghavan P, Holder CA, Rubin D, Huang E, Kirby J, Freymann J, Jaffee CC, Flanders A, Zinn PO. Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group project.BMC Medical Genomics, 2014. 7(1):30. DOI: 10.1186/1755-8794-7-30 (link)
  21. Gevaert O, Mitchell LA, Achrol AS, Xu J, Echegaray S, Steinberg GK, Chesier SH, Napel S, Zaharchuk G, Plevritis SK. Glioblastoma Multiforme: Exploratory Radiogenomic Analysis by Using Quantitative Image Features. Radiology, 2014. doi: 10.1148/radiol.14131731 (link)
  22. Mazurowski MA, Zhang J, Peters KB, and Hobbs H. Computer-extracted MR imaging features are associated with survival in glioblastoma patients. Journal of Neuro-Oncology, 2014. 120(3):483–488 DOI: 10.1007/s11060-014-1580-5 (link)
  23. Jain R, Poisson L, Gutman D, Scarpace L, Hwang SN, Holder C, Wintermark M, Colen RR, Kirby J, Freymann J, Jaffe C, Mikkelsen T, Flanders A. Outcome Prediction in Patients with Glioblastoma by Using Imaging, Clinical, and Genomic Biomarkers: Focus on the Nonenhancing Component of the Tumor. Radiology. 2014 Aug;272(2):484-93. doi: 10.1148/radiol.14131691. Epub 2014 Mar 19. 2014 (link)
  24. Nicolasjilwan M, Hu Y, Yan C, Meerzaman D, Holder CA, Gutman D, et al. Addition of MR imaging features and genetic biomarkers strengthens glioblastoma survival prediction in TCGA patients. Journal of Neuroradiology, July 2014. doi: 10.1016/j.neurad.2014.02.006

  27. Kwon D, Shinohara RT, Akbari H, Davatzikos C. Combining Generative Models for Multifocal Glioma Segmentation and Registration.  Medical Image Computing and Computer-Assisted Intervention–MICCAI 2014: Springer; 2014. p. 763-70.

  30. Gutman DA, Cooper LAD, Hwang SN, Holder CA, Gao J, Aurora TD, Dunn WD, Scarpace L, Mikkelsen T, Jain R, Wintermark M, Jilwan M, Raghavan P, Huang E, Clifford RJ, Monqkolwat P, Kleper V, Freymann J, Kirby J, Zinn PO, Moreno CS, Jaffe C, Colen R, Rubin DL, Saltz J, Flanders A, Brat DJ. MR Imaging Predictors of Molecular Profile and Survival: Multi-institutional Study of the TCGA Glioblastoma Data Set. Radiology. 2013 May:267(2):560-569,doi:10.1148/radiol.13120118 (link)
  31. Jain R, Poisson L, Narang J, Gutman D, Scarpace L, Hwang SN, Holder C, Wintermark M, Colen RR, Kirby J, Freymann J, Brat DJ, Jaffe C, Mikkelsen T. Genomic Mapping and Survival Prediction in Glioblastoma: Molecular Subclassification Strengthened by Hemodynamic Imaging Biomarkers. Radiology, 2013 Apr:267(1):212 –220, doi:10.1148/radiol.12120846 (link)
  32. Mazurowski MA, Desjardins A, Malof JM. Imaging descriptors improve the predictive power of survival models for glioblastoma patients. Neuro-oncology, 2013. 15(10):1389-1394 (link)
  33. Zinn PO, Colen RR. Imaging Genomic Mapping in Glioblastoma. Neurosurgery 60:126-130. Aug 2013 (link)
  34. Jain R, Poisson L, Narang J, Scarpace L, Rosenblum ML, Rempel S, Mikkelson T. Correlation of Perfusion Parameters with Genes Related to Angiogenesis Regulation in Glioblastoma: A Feasibility Study. American Journal of Neuroradiology, 2012. 33(7):1343-1348 [Epub ahead of print] (link)
  35. Zinn PO, Sathyan P, Mahajan B, Bruyere J, Hegi M, et al. A Novel Volume-Age-KPS (VAK) Glioblastoma Classification Identifies a Prognostic Cognate microRNA-Gene Signature. PLoS ONE, 2012 7(8): e41522. doi:10.1371/journal.pone.0041522 (link)
  36. Zinn PO, Majadan B, Sathyan P, Singh SK, Majumder S, et al. Radiogenomic Mapping of Edema/Cellular Invasion MRI-Phenotypes in Glioblastoma Multiforme. PLoS ONE, 2011 6(10): e25451. doi:10.1371/journal.pone.0025451 (link)
  37. Wangaryattawanich, P., M. Hatami, et al.  "Multicenter imaging outcomes study of The Cancer Genome Atlas glioblastoma patient cohort: imaging predictors of overall and progression-free survival." Neuro-oncology, (2015): nov117 .

  38. Kuo, J. S., K. B. Pointer, et al. (2015). "139 Human Ether-a-Go-Go-Related-1 Gene (hERG) K+ Channel as a Prognostic Marker and Therapeutic Target for Glioblastoma." Neurosurgery 62: 210-211.

  39. Zinn, P. O., M. Hatami, et al. (2015). "138 Diffusion MRI ADC Mapping of Glioblastoma Edema/Tumor Invasion and Associated Gene Signatures." Neurosurgery 62: 210.

  40. Steed, T., J. Treiber, et al. (2015). "Iterative Probabilistic Voxel Labeling: Automated Segmentation for Analysis of The Cancer Imaging Archive Glioblastoma Images." American Journal of Neuroradiology 36(4): 678-685.

  41. Lee, J., S. Narang, et al. (2015). "Associating spatial diversity features of radiologically defined tumor habitats with epidermal growth factor receptor driver status and 12-month survival in glioblastoma: methods and preliminary investigation." Journal of Medical Imaging 2(4): 041006-041006.

  42. Itakura, H., A. S. Achrol, et al. (2015). "Magnetic resonance image features identify glioblastoma phenotypic subtypes with distinct molecular pathway activities." Science Translational Medicine 7(303): 303ra138-303ra138.

  43. Cui, Y., K. K. Tha, et al. (2015). "Prognostic Imaging Biomarkers in Glioblastoma: Development and Independent Validation on the Basis of Multiregion and Quantitative Analysis of MR Images." Radiology: 150358.

  44. Lee, J., S. Narang, et al. (2015). "Spatial Habitat Features Derived from Multiparametric Magnetic Resonance Imaging Data Are Associated with Molecular Subtype and 12-Month Survival Status in Glioblastoma Multiforme." PloS one 10(9): e0136557.

  45. Rios Velazquez E, Meier R, Dunn WD Jr, Alexander B, Wiest R, Bauer S, Gutman DA, Reyes M, Aerts HJ. "Fully automatic GBM segmentation in the TCGA-GBM dataset: Prognosis and correlation with VASARI features." Sci Rep. 2015 Nov 18;5:16822. doi: 10.1038/srep16822.
  46. Liu, Y., Xu, X., Yin, L., Zhang, X., Li, L., & Lu, H. (2017). Relationship between glioblastoma heterogeneity and survival time: An MR imaging texture analysis. American Journal of Neuroradiology, 1-7. doi:10.3174/ajnr.A5279.

  47. ParthaSarathi, M., & Ansari, M. A. (2017). Multimodal retrieval framework for brain volumes in 3D MR volumes. Journal of Medical and Biological Engineering, 1-12. doi:10.1007/s40846-017-0287-4

Collection: TCGA-KIRC 

  1. Chen X, Zhou Z, Thomas K, Wang J. Predicting Gene Mutations in Renal Cell Carcinoma Based On CT Imaging Features: Validation Using TCGA-TCIA Datasets. Med. Phys. 43, 3705 (2016); (link)
  2. Zhu H, Chen H, Lin Z, Shi G, Lin X, Wu Z, Zhang X. Identifying molecular genetic features and oncogenic pathways of clear cell renal cell carcinoma through the anatomical (PADUA) scoring system. Oncotarget. 2016. (link)
  3. Shinagare AB, Vikram R, Jaffe C, Akin O, Kirby J, Huang E, Freymann J, Sainani NI, Sadow CA, Bathala TK. Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas–Renal Cell Carcinoma (TCGA–RCC) Imaging Research Group. Abdominal imaging. 2015:1-9.

Collection: 4D-Lung 

  1. Woodruff, H. C., Shieh, C.-C., Hegi-Johnson, F., Keall, P. J. and Kipritidis, J. (2017), Quantifying the reproducibility of lung ventilation images between 4-Dimensional Cone Beam CT and 4-Dimensional CT. Med. Phys. DOI: 10.1002/mp.12199
  2. Hugo GD, Weiss E,  Sleeman WC, Balik S, Keall PJ, Lu J, Williamson JF. A longitudinal four-dimensional computed tomography and cone beam computed tomography dataset for image-guided radiation therapy research in lung cancer. Med. Phys. (2017) doi: 10.1002/mp.12059