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The American College of Radiology Imaging Network (ACRIN) trial 6698 (NCT01564368) was a multi-center study to evaluate the effectiveness of quantitative diffusion weighted imaging (DWI) for assessing breast cancer response to neoadjuvant chemotherapy (NAC). ACRIN 6698 was performed as a sub-study of the ongoing I-SPY 2 TRIAL (Investigation of Serial studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2), an adaptive, multi-agent phase II trial designed to quickly identify new agents for breast cancer.
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