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The National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) is a national effort to accelerate the understanding of the molecular basis of cancer through the application of large-scale proteome and genome analysis, or proteogenomics. Data (genomics, proteomics, imaging), assays, and reagents are made available to the public as a Community Resource to accelerate cancer research and advance patient care. |
CPTAC has been conducted in multiple phases. For the phase 3 prospective data collection activities TCIA has partnered with CPTAC to host both the radiology and pathology imaging data generated by the project. The other data types will be hosted in separate databases managed by the CPTAC program. TCIA will provide links to these resources as they become publicly available.
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You can join the CPTAC Imaging Special Interest Group to be notified of webinars & data releases, collaborate on common data wrangling tasks and seek out partners to explore research hypotheses! |
CPTAC
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Imaging Discovery Cohorts
CPTAC imaging data is being made available on a quarterly release schedule that is coordinated with the CPTAC program releases of proteomic and genomic data. Learn more about each cancer type by clicking on the collection names in the table below. Data currently available is listed below. Clicking on the number of subjects will take you to these data portals with that particular cancer type pre-selected. You can access the radiology and pathology data directly from the respective data portals. Learn more about the CPTAC Discovery data sets here.
Collection | Cancer Type | Location | Radiology Modalities | Radiology (Subjects)* | Pathology (Subjects)** |
Clear Cell Carcinoma | Kidney | CR, CT, DX, MR, SR | 222 |
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Cutaneous Melanoma
Skin
CR, CT, MR
Glioblastoma Multiforme | Brain | CR, CT, DX, MR, NM, SC | 189 | ||
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CPTAC-HNSCC | Head and Neck Squamous Cell Carcinoma | Head-Neck | CT, SC, MR | 64 | 112 |
Squamous Cell Carcinoma | Lung | CR, CT, DX, NM, PT | 212 | ||
Adenocarcinoma | Lung | CT, MR, PT, CR, DX, NM | 244 | ||
Ductal Adenocarcinoma
Corpus Endometrial Carcinoma | Uterus | CT, MR, |
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PT, CR, |
DX |
250 | |||||
CPTAC-BRCA (coming soon) | Breast Invasive Carcinoma | Breast | N/A | 0 | 198 |
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CPTAC- |
COAD (coming soon) | Colon Adenocarcinoma | Colon | N/A | 0 | 179 |
CPTAC-OV (coming soon) | Ovarian Serous Cystadenocarcinoma | Ovary | N/A | 0 | 73 |
Corpus Endometrial Carcinoma
Uterus
CT, MR, PT, CR, DX
*links go to TCIA NBIA radiological search portal
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CPTAC
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- TCGA Cancer Proteome Studies
TCIA did not formally participate in CPTAC phase 2, but a small subset of the radiology imaging studies for this cohort are available due to overlap with NIH's Cancer Genome Atlas activity. Specifically there There are 28 ovarian (TCGA-OV) and 14 breast (TCGA-BRCA) cases in TCIA which have corresponding CPTAC phase 2 proteomic analysis data. The Proteomic Analysis Data is available at: https://cptac-data-portal.georgetown.edu/cptacPublic/.
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