This study was a multi-reader, multi-institutional, IRB-approved retrospective analysis of 93 HGSOC patients with abdominal and pelvic CT scans prior to primary debulking that were available through The Cancer Imaging Archive (TCIA). Eight radiologists from The Cancer Genome Atlas-Ovarian Cancer (TCGA-OV) Imaging Research Group developed and subsequently independently recorded the following CT features in each patient: primary ovarian mass(es) characteristics (if present), presence and distribution of peritoneal tumor spread, lymphadenopathy, and distant metastases. Inter-observer agreement for the CT features was assessed, as were associations of these features with time-to-disease progression (TTP) and CLOVAR subtypes and abilities of combinations of these features to predict TTP and CLOVAR subtypes. Results of analyzing this data are published in a manuscript titled Radiogenomics of High-Grade Serous Ovarian Cancer: Multi- Reader Multi-Institutional Study from The Cancer Genome Atlas-Ovarian Cancer (TCGA-OV) Imaging Research Group.
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|Data Type||Download all or Query/Filter|
(Needs NBIA Data Retriever)
Full Radiologist Assessments of Image Features (CSV)
Consensus Radiologist Assessments of Image Features (CSV)
|Clinical data (CSV)|
|Genomic sub-type data (CSV)|
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Collections Used in this Third Party Analysis
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Citations & Data Usage Policy
Users of this data must abide by the TCIA Data Usage Policy and the Creative Commons Attribution 3.0 Unported License under which it has been published. Attribution should include references to the following citations:
Vargas, A., Huang, E., Lakhman, Y., Ippolito, J., Bhosale, P., Mellnick, V., Shinagare, A., Anello, M., Kirby, J., Fevrier-Sullivan, B., Freymann, J., Jaffe, C., & Sala, E. (2016). Imaging Features, and Correlations with Genomic and Clinical Data from the TCGA Ovarian Radiology Research Group. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2016.PSJOXM47
Vargas, H. A., Huang, E. P., Lakhman, Y., Ippolito, J. E., Bhosale, P., Mellnick, V., Shinagare, A. B., Anello, M., Kirby, J., Fevrier-Sullivan, B., Freymann, J., Jaffe, C. C., & Sala, E. (2017). Radiogenomics of High-Grade Serous Ovarian Cancer: Multireader Multi-Institutional Study from the Cancer Genome Atlas Ovarian Cancer Imaging Research Group. Radiology, 285(2), 482-492. https://doi.org/10.1148/radiol.2017161870
Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. Journal of Digital Imaging, 26(6), 1045–1057. https://doi.org/10.1007/s10278-013-9622-7