Summary
This collection of soft-tissue sarcoma dynamic contrast-enhanced (DCE) MRI data contains images from a longitudinal study to assess soft-tissue sarcoma response to preoperative chemoradiation treatment. Images were acquired at three time points: prior to the start of treatment (Visit 1, V1), after the first cycle of chemotherapy (Visit 2, V2), and after ~ 8 more weeks of chemoradiation (prior to surgery) (Visit 3, V3). Not every patient was able to complete all three MRI studies. The value of this collection is to provide clinical imaging data for the development and validation of quantitative imaging methods for assessment of soft-tissue sarcoma response to preoperative treatment. Initial findings of this study have been published and the data is provided by Oregon Health & Science University, PI Dr. Wei Huang. The MRI data consist of DCE-MRI images only, which were acquired using a Siemens 3T TIM Trio system with the body coil as the transmitter and a body matrix phased array (combined with a spine matrix phased array) coil as the receiver. Following scout and axial T2-weighted MRI, a RF-spoiled gradient-echo sequence was used to acquire sagittal DCE-MRI images covering the entire tumor, with 100 flip angle, TE/TR = 1.5/6.0 ms, 24-26 cm field of view (FOV), and 5 mm slice thickness with 1 mm gap. A parallel imaging acceleration factor of 2 was used for DCE-MRI, resulting in 7-16 s temporal resolutions depending on tumor size. The total DCE acquisition time was approximately 10 min with gadolinium contrast agent (Prohance®) IV injection (0.1 mmol/kg at 2 mL/s) carried out following acquisition of five baseline image volumes, followed by a 20-mL saline flush.
Data Access
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Data Type | Download all or Query/Filter | License |
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Images (DICOM, 10.29GB) |
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Detailed Description
Collection Statistics | Radiology Imaging Statistics |
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Modalities | MR |
Number of Patients | 15 |
Number of Studies | 38 |
Number of Series | 2,168 |
Number of Images | 46,614 |
Image Size (GB) | 10.29 |
Citations & Data Usage Policy
Users must abide by the TCIA Data Usage Policy and Restrictions. Attribution should include references to the following citations:
Data Citation
Huang, W., Ryan, C., Beckett, B., Tudorica, A., Mansoor, A., Afzal, A., Holtorf, M., & Aston, T. (2016). QIN-SARCOMA [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2016.fXL9sESs
Funding Acknowledgement
Please be sure to include the following citations in your work and acknowledge the award that supported collection and sharing of these data sets (U01 CA154602, PI: Wei Huang) if you use this data set.
Publication Citation
Meyer, J. M., Perlewitz, K. S., Hayden, J. B., Doung, Y.-C., Hung, A. Y., Vetto, J. T., Pommier, R. F., Mansoor, A., Beckett, B. R., Tudorica, A., Mori, M., Holtorf, M. L., Afzal, A., Woodward, W. J., Rodler, E. T., Jones, R. L., Huang, W., & Ryan, C. W. (2013). Phase I Trial of Preoperative Chemoradiation plus Sorafenib for High-Risk Extremity Soft Tissue Sarcomas with Dynamic Contrast-Enhanced MRI Correlates. In Clinical Cancer Research (Vol. 19, Issue 24, pp. 6902–6911). American Association for Cancer Research (AACR). https://doi.org/10.1158/1078-0432.ccr-13-1594 PMCID: PMC3869565
TCIA Citation
Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045–1057). Springer Science and Business Media LLC. https://doi.org/10.1007/s10278-013-9622-7 PMCID: PMC3824915
Other Publications Using This Data
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Version 1 (Current): Updated 2014/09/04
Data Type | Download all or Query/Filter |
---|---|
Images (DICOM, 10.29GB) |
(Download requires the NBIA Data Retriever.) |