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Summary

Excerpt

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This collection contains data from the Eastern Cooperative Oncology Group (ECOG

-ACRIN Cancer Research Group

) Clinical Trial NCT02933489, “

Comparison of

Abbreviated Breast MRI and Digital

Breast

Tomosynthesis Mammography in

Breast Cancer

Screening

in

Women With Dense Breasts"

,  Principal

. Principle Investigator: Christopher Comstock

, MD

.  It was sponsored by NCI and performed by the

ECOG-ACRIN Cancer Research Group

 Eastern Cooperative Oncology Group under study number EA1141. This randomized phase II trial

studies

enrolled 1,516 subjects to study how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts.

Abbreviated breast MRI is a low cost procedure in which radio waves and a powerful magnet linked to a computer and used to create detailed pictures of the breast in less than 10 minutes. These pictures can show the difference between normal and diseased tissue. Digital tomosynthesis mammography is a procedure that uses multiple x-rays pictures of each breast to produce a 3-dimensional rendering of the entire breast. Combined screening with abbreviated breast MRI and digital tomosynthesis mammography may be a better method to screen women with dense breasts. Select patient-level clinical data from this trial is available via the following link: (not sure).

Imaging and clinical data from 500 of those subjects are being made available through this collection.

Trial Outcomes

Results of the trial have been reported in the following publication:

  • Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK. Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. JAMA. 2020 Feb 25;323(8):746-756. doi: 10.1001/jama.2020.0572. Erratum in: JAMA. 2020 Mar 24;323(12):1194. 


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titleData Access

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Clinical data (CSV, zip)


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Nctn additional resources

NCTN/NCORP Data Archive (Clinical Data)


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titleDetailed Description

Detailed Description

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Radiology Image Statistics

Modalities


Number of Patients


Number of Studies


Number of Series


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National Clinical Trials Network (NCTN) Date Handling


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titleCitations & Data Usage Policy

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titleData Citation

DOI goes here. 


Info
titlePublication Citation

Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK. Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. JAMA. 2020 Feb 25;323(8):746-756. doi: 10.1001/jama.2020.0572. Erratum in: JAMA. 2020 Mar 24;323(12):1194. 


Info
titleTCIA Citation

Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045–1057). Springer Science and Business Media LLC.https://doi.org/10.1007/s10278-013-9622-7

Other Publications Using This Data

TCIA maintains a list of publications which leverage TCIA data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.


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titleVersions

Version 1 (Current): Updated 2023/mm/dd

Data TypeDownload all or Query/FilterLicense

Images (DICOM, XX.X GB)



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Clinical data (CSV, zip)


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urlhttps://wiki.cancerimagingarchive.net/download/attachments/157286463/EA1141%20Reviewed%20Clinical%20Data%20%20and%20Data%20Dictionaries.zip?api=v2



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