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  • Cancer Moonshot Biobank - Colorectal Cancer Collection (CMB-CRC)

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Image ModifiedThe Cancer Moonshot Biobank was started by the is a National Cancer Institute to help researchers better understand and treat cancer. The Moonshot Biobank will ask cancer patients across the United States to donate biospecimens (blood and small pieces of initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens (blood and tissue removed during medical procedures) and associated health information. The Moonshot Biobank will collect biospecimens longitudinally, that is, over the whole period of time that a person is getting cancer treatment. The biospecimens and associated health information will be made available to qualified cancer scientists to help those researchers learn how cancer grows and changes in people, and to find new cancer treatments. To help make sure that cancer patients from all population groups can potentially benefit from the research, cancer patients from diverse racial, cultural, ethnic and socioeconomic groups will be asked to participate in the Biobank.This 5-year effort will support cancer research by establishing an infrastructure for longitudinal biospecimen collections from a diverse patient population data will be collected longitudinally from at least 1000 patients (across at least 10 cancer types), who represent the demographic diversity of the U.S. and receiving standard of care cancer treatment at multiple NCI Community Oncology Research Program (NCORP) sites.

This collection contains subjects from NCI’s Cancer Moonshot Biobank (insert cancer type and collection name, for eg. "Colorectal Cancer (CMB-CRC)") cohort. De-identified radiology and histopathology imaging procured from patients receiving standard of care treatment will be made available on The Cancer Imaging Archive (TCIA). Associated genomic, phenotypic and clinical data will be hosted by The Database of Genotypes and Phenotypes (dbGaP) and other NCI databases medical institutions. The Moonshot Biobank will work in collaboration with community hospitals to engage eligible patients and collect biospecimens and associated data. Samples will be stored at a central location (biobank). The biobank will perform pathology quality control and distribute biospecimens. A clinical laboratory will perform genetic testing on tumor tissue and return results to the participant's healthcare provider. The tumor genetic test results may provide more information for cancer treatment decisions and may help researchers better understand how genes within a tumor can affect cancer progression and treatment.

For more information visit: https://moonshotbiobank.cancer.gov/

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