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This dataset contains images from 31 out of the 32 non-small cell lung cancer (NSCLC) patients in the RIDER Lung CT collection on TCIA. For these subjects a radiation oncologist was blinded to the all delineations of the 3D volume of the gross tumor volume. They were then asked to manually delineate the gross tumour volume in both the test image and the re-test image. The process was repeated using an in-house autosegmentation method. There is no clinical outcome data associated with this dataset. This dataset refers to the RIDER dataset of the study published in Nature Communications (http://doi.org/10.1038/ncomms5006). In short, this publication used the dataset to select for repeatable radiomics features in a test-retest context. Radiomics refers to the comprehensive quantification of tumour phenotypes by applying a large number of quantitative image features. In the published analysis, 440 features quantifying tumour image intensity, shape and texture, were extracted. We found that a large number of radiomic features have prognostic power in independent data sets, many of which were not identified as significant before. Radiogenomics analysis revealed that a prognostic radiomic signature, capturing intra-tumour heterogeneity, was associated with underlying gene-expression patterns. These data suggest that radiomics identifies a general prognostic phenotype existing in both lung and head-and-neck cancer. This may have a clinical impact as imaging is routinely used in clinical practice, providing an unprecedented opportunity to improve decision-support in cancer treatment at low cost. |
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Other data sets in the Cancer Imaging Archive that were used in the same study published in Nature Communications: NSCLC-Radiomics, NSCLC-Radiomics-Genomics, NSCLC-Radiomics-Interobserver1, HEAD-NECK-RADIOMICS-HN1.
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title | Data Access |
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| Data AccessData Type | Download all or Query/Filter | License |
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Gross Tumor Volume Segmentation - (DICOM RTSTRUCT and SEG, 912 MB) |
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url | https://wiki.cancerimagingarchive.net/download/attachments/46334165/RIDER%20Lung%20CT%20RTSTRUCTS%20DICOM%20SEGS%20Leonard%20Wee%20Feb%2010%202020.tcia?api=v2 |
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Collections Used in this Third Party AnalysisBelow is a list of the Collections used in these analyses: Source Data Type | Download all or Query/Filter | License |
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Corresponding Original CT Images from RIDER Lung CT - (DICOM, 7 GB) |
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url | https://wiki.cancerimagingarchive.net/download/attachments/46334165/RIDER%20Lung%20CT%20Original%20Scans%20for%20Leonard%20Wee%20Feb%2010%202020%20.tcia?api=v2 |
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title | Detailed Description |
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| Detailed DescriptionImage Statistics |
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Modalities (DICOM) | RTSTRUCT, SEG | Number of Patients | 31 | Number of Studies | 31 | Number of Series | 118 | Number of Images | 118 | Images Size (GB) | 912 MB |
(RIDER-2283289298) only has segmentations associated with the retest. (RIDER-5195703382) only has segmentations associated with the test. (RIDER-8509201188) only has segmentations associated with the test. (RIDER-9762593735) not included in the data set due to missing delineations.
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title | Citations & Data Usage Policy |
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| Citations & Data Usage Policy Tcia limited license policy |
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Description
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| Wee, L., Aerts, H., Kalendralis, P., & Dekker, A. (2020). RIDER Lung CT Segmentation Labels from: Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/tcia.2020.jit9grk8 |
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| Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. Journal of Digital Imaging, 26(6), 1045–1057. https://doi.org/10.1007/s10278-013-9622-7 |
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title | Publication Citation |
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| Aerts, H. J. W. L., Velazquez, E. R., Leijenaar, R. T. H., Parmar, C., Grossmann, P., |
| Cavalho, S., … Carvalho, S., Bussink, J., Monshouwer, R., Haibe-Kains, B., Rietveld, D., Hoebers, F., Rietbergen, M. M., Leemans, C. R., Dekker, A., Quackenbush, J., Gillies, R. J., & Lambin, P. (2014 |
| , June 3). Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nature Communications |
| . Nature Publishing Group. http
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| Version 2 (Current): Updated 2021/10/28Data Type | Download all or Query/Filter |
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Gross Tumor Volume Segmentation - (DICOM RTSTRUCT and SEG, 912 MB) |
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The authors of this dataset agreed to change the license to permit commercial use. The actual dataset remains unchanged. Version 1: Updated 2020/02/13Data Type | Download all or Query/Filter |
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Gross Tumor Volume Segmentation - (DICOM RTSTRUCT and SEG, 912 MB) | | Corresponding Original CT Images from RIDER Lung CT - (DICOM, 7 GB) | |
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