Summary
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This data collection consists of images acquired during chemoradiotherapy of 20 locally-advanced, non-small cell lung cancer patients. The images include four-dimensional (4D) fan beam (4D-FBCT) and 4D cone beam CT (4D-CBCT). All patients underwent concurrent radiochemotherapy to a total dose of 64.8-70 Gy using daily 1.8 or 2 Gy fractions. |
This data collection consists of images acquired during chemoradiotherapy of 20 locally-advanced, non-small cell lung cancer patients. The images include four-dimensional (4D) fan beam (4D-FBCT) and 4D cone beam CT (4D-CBCT). A single Radiation Oncologist delineated targets and organs at risk in all 4D-FBCT and a limited number of 4D-CBCT images. All patients underwent concurrent radiochemotherapy to a total dose of 64.8-70 Gy using daily 1.8 or 2 Gy fractions. The dataset is more fully described in the ‘Description’ section below.
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Data AccessThis is a limited access data set. To request access, please contact help@cancerimagingarchive.net. Once access is granted, you can view and download these images on The Cancer Imaging Archive (TCIA) by logging in and selecting the 4D-Lung collection. Click the Versions tab for more info about data releases. |
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| title | Detailed Description |
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Detailed Description
Collection Statistics | Update 09/14/2015 |
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Modalities | CT, RTSTRUCT |
Number of Patients | 20 |
Number of Studies | 589 |
Number of Series | 6,690 |
Number of Images | 347,330 |
| Image Size (GB) |
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This data collection consists of images acquired during chemoradiotherapy of 20 locally-advanced, non-small cell lung cancer patients. The images include four-dimensional (4D) fan beam (4D-FBCT) and 4D cone beam CT (4D-CBCT). All patients underwent concurrent radiochemotherapy to a total dose of 64.8-70 Gy using daily 1.8 or 2 Gy fractions. |
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4D-FBCT images were acquired on a 16-slice helical CT scanner (Brilliance Big Bore, Philips Medical Systems, Andover, MA) as respiration-correlated CTs with 10 breathing phases (0 to 90%, phase-based binning) and 3 mm slice thickness. 4D-FBCT images were acquired during simulation, prior to therapy, and used for therapy planning. In 14 of the 20 subjects, 4D-FBCTs were also acquired on the same scanner weekly during therapy. 4D-CBCT images were acquired on a commercial CBCT scanner (On-Board Imager™, Varian Medical Systems, Inc.). An external surrogate (Real-time Position Management, Varian Medical Systems, Inc.) was integrated into the CBCT acquisition system to stamp each CBCT projection with the surrogate respiratory signal through in-house software and hardware tools. Approximately 2500 projections were acquired over a period of 8-10 minutes in half-fan mode with half bow-tie filter. The technique was 125 kVp, 20 mA, and 20 ms in a single 360° slow gantry arc. Using the external surrogate, the CBCT projections were sorted into 10 breathing phases (0 to 90%, phase-based binning) and reconstructed with an in-house FDK reconstruction algorithm. Audio-visual biofeedback was performed for all 4D-FBCT and 4D-CBCT acquisitions in all subjects. A single Radiation Oncologist delineated targets and organs at risk in all 4D-FBCT and a limited number of 4D-CBCT images, on all 10 phases per scan. Seven of the subjects had gold coils implanted as fiducial markers in or near the tumor. |
The dataset is most fully described in detail in Balik et al.1 Seven of the subjects had gold coils implanted as fiducial markers in or near the tumor. The implantation procedure and details of marker location are described in detail in Roman et al.2
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For questions and information regarding this dataset, please contact Geoff Hugo, gdhugo@vcu.edu.
Data collection and analysis was supported by NIH P01CA116602.
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| title | Citations & Data Usage Policy |
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Citations & Data Usage Policy
This is a limited access data set. Upon receiving access you may only use it for the purposes outlined in your request to the data provider. You are not allowed to redistribute the data or use it for other purposes. See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.
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The Cancer Imaging Archive Team. Data From 4D-Lung. (DOI coming soon)
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Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper) |
Other Publications Using This Data
TCIA maintains a list of publications which leverage our data. At this time we are not aware of any publications based on this data. If you have a publication you'd like to add please contact the TCIA Helpdesk.
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Acknowledgements
Data collection and analysis was supported by NIH P01CA116602.
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| title | Description |
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Collection Statistics
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(updated 2015/09/14)
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This data collection consists of images acquired during chemoradiotherapy of 20 locally-advanced, non-small cell lung cancer patients. The images include four-dimensional (4D) fan beam (4D-FBCT) and 4D cone beam CT (4D-CBCT). All patients underwent concurrent radiochemotherapy to a total dose of 64.8-70 Gy using daily 1.8 or 2 Gy fractions. The dataset -- including 4D fan and cone beam CT technique and collection protocol, delineation protocol, an -- is most fully described in detail in Balik et al.1 Briefly, 4D-FBCT images were acquired on a 16-slice helical CT scanner (Brilliance Big Bore, Philips Medical Systems, Andover, MA) as respiration-correlated CTs with 10 breathing phases (0 to 90%, phase-based binning) and 3 mm slice thickness. 4D-FBCT images were acquired during simulation, prior to therapy, and used for therapy planning. In 14 of the 20 subjects, 4D-FBCTs were also acquired on the same scanner weekly during therapy. 4D-CBCT images were acquired on a commercial CBCT scanner (On-Board Imager™, Varian Medical Systems, Inc.). An external surrogate (Real-time Position Management, Varian Medical Systems, Inc.) was integrated into the CBCT acquisition system to stamp each CBCT projection with the surrogate respiratory signal through in-house software and hardware tools. Approximately 2500 projections were acquired over a period of 8-10 minutes in half-fan mode with half bow-tie filter. The technique was 125 kVp, 20 mA, and 20 ms in a single 360° slow gantry arc. Using the external surrogate, the CBCT projections were sorted into 10 breathing phases (0 to 90%, phase-based binning) and reconstructed with an in-house FDK reconstruction algorithm.
Audio-visual biofeedback was performed for all 4D-FBCT and 4D-CBCT acquisitions in all subjects. A single Radiation Oncologist delineated targets and organs at risk in all 4D-FBCT and a limited number of 4D-CBCT images, on all 10 phases per scan. Seven of the subjects had gold coils implanted as fiducial markers in or near the tumor. The implantation procedure and details of marker location are described in detail in Roman et al.2
For questions and information regarding this dataset, please contact Geoff Hugo, gdhugo@vcu.edu.
Data collection and analysis was supported by NIH P01CA116602.
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