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Summary

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locationhttps://www.cancerimagingarchive.net/collection/ea1141/
Image AddedThis collection contains data from theEastern the Eastern Cooperative Oncology Group (ECOG-ACRIN Cancer Research Group ) Clinical Trial NCT02933489, “Comparison of Abbreviated Breast MRI and Digital Breast Tomosynthesis Mammography in Breast Cancer Screening in Women With Dense Breasts",  Principal . Principle Investigator: Christopher Comstock, MD.  It was sponsored by NCI and performed by the ECOG-ACRIN Cancer Research Group  Eastern Cooperative Oncology Group under study number EA1141. This randomized phase II trial studies enrolled 1,516 subjects to study how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts. Abbreviated breast MRI is a low cost procedure in which radio waves and a powerful magnet linked to a computer and used to create detailed pictures of the breast in less than 10 minutes. These pictures can show the difference between normal and diseased tissue. Digital tomosynthesis mammography is a procedure that uses multiple x-rays pictures of each breast to produce a 3-dimensional rendering of the entire breast. Combined screening with abbreviated breast MRI and digital tomosynthesis mammography may be a better method to screen women with dense breasts. Select patient-level clinical data from this trial is available via the following link: (not sure).

                                                                                                                                                                                                                                                                                                                                                                                                                         Image Removed

                                                                                                                                                                                                                                                                                                                                                   

Imaging and clinical data from 500 of those subjects are being made available through this collection.

Trial Outcomes

Results of the trial have been reported in the following publication:

  • Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK. Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. JAMA. 2020 Feb 25;323(8):746-756. doi: 10.1001/jama.2020.0572. Erratum in: JAMA. 2020 Mar 24;323(12):1194. 


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titleData Access

Data Access

This is a limited access data set. To request access please register an account on the NCTN
Data
Archive.  After logging in, use the "Request Data" link in the left side menu.  Follow the on screen instructions, and enter NCT02933489 when asked which trial you want to request.  In step 2 of the Create Request form, be sure to select “Imaging Data Requested”. Please contact NCINCTNDataArchive@mail.nih.gov for any questions about access requests.
Data
TypeDownload all or Query/FilterLicense

Images

, Segmentations, and Radiation Therapy Structures/Doses/Plans

(DICOM,

XX

2.

X GB

82 TB)

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Clinical data (CSV, zip, 1.69 MB)


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Clinical data (CSV)
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Additional Resources for this Dataset

Nci_crdc additional resources

Nctn additional resources

Include PageNational Clinical Trials Network (NCTN) Date HandlingNational Clinical Trials Network (NCTN) Date Handling


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titleDetailed Description

Detailed Description

Image Statistics

Radiology Image StatisticsPathology Image Statistics

Modalities

CT, MG, MRModalities

Number of Patients

500

Number of Studies

1976

Number of Series

14340

Number of Images

855193

Images Size (GB)

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National Clinical Trials Network (NCTN) Date Handling
2,820

De-identification of DICOM dates

De-identification of dates for this dataset was done prior to receipt and curation by TCIA in a method similar to the TCIA process. TCIA uses the DICOM Part 3.15 Annex E standard “Retain Longitudinal With Modified Dates Option” which allows dates to be retained as long as they are modified from the original date.  TCIA implements this using a technique which de-identifies the dates while preserving the longitudinal relationship between them.  Original dates were first normalized to 01 January, 1945 and then offset relative to the date of registration for each patient.  This normalized date system was chosen in order to make it obvious that the dates are not real, and to make it easy to quickly determine how much time has passed between the date of registration and the patients' related imaging studies. 

For example, if the real date of a patient's registration was 03/27/2018 and the original imaging Study Date was 03/29/2018 then the "Days from registration" would be +2 and the anonymized TCIA Study Date would become 01/03/1945.

Insertion of computed "REGISTRATION"/Days offset from registration" value

In addition to modifying the actual date fields in the DICOM header, the "days from registration" values are calculated and stored in the DICOM tag (0012,0052) Longitudinal Temporal Offset from Event with the associated tag (0012,0053) Longitudinal Temporal Event Type set to “REGISTRATION”. 

Note: If these DICOM tags are not present, DICOM tag (0012,0050) Clinical Trial Time Point ID with the associated tag (0012,0051) Clinical Trial Time Point Description provides this same information.  This inconsistency is due to a change in how dates were handled in the first NCTN trials that were published on TCIA.

National Clinical Trials Network (NCTN) Date Handling


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titleCitations & Data Usage Policy

Citations & Data Usage Policy

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titleData Citation

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titlePublication Citation

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Comstock, C. E., Gatsonis, C., Newstead, G. M., Snyder, B. S., Gareen, I. F., Bergin, J. T., Rahbar, H., Sung, J. S., Jacobs, C., Harvey, J. A., Nicholson, M. H., Ward, R. C., Holt, J., Prather, A., Miller, K. D., Schnall, M. D., & Kuhl, C. K. (2023). Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts (EA1141) (Version 1) [dataset]. The Cancer Imaging Archive. https://doi.org/10.7937/2BAS-HR33


Info
titlePublication Citation

Comstock, C. E., Gatsonis, C., Newstead, G. M., Snyder, B. S., Gareen, I. F., Bergin, J. T., Rahbar, H., Sung, J. S., Jacobs, C., Harvey, J. A., Nicholson, M. H., Ward, R. C., Holt, J., Prather, A., Miller, K. D., Schnall, M. D., & Kuhl, C. K. (2020). Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. In JAMA (Vol. 323, Issue 8, p. 746). American Medical Association (AMA). https://doi.org/10.1001/jama.2020.0572

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titleAcknowledgement

Required acknowledgements only (ex:The CPTAC program requests that publications using data from this program...). If they just want to thank someone, that goes in the Acknowledgement section underneath the Summary.


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titleTCIA Citation

Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045–1057). Springer Science and Business Media LLC.https://doi.org/10.1007/s10278-013-9622-7

Other Publications Using This Data

TCIA maintains a list of publications which leverage TCIA data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.


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titleVersions

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1 (Current): Updated

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2023/

mm

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dd

02

Data TypeDownload all or Query/FilterLicense

Images

, Segmentations, and Radiation Therapy Structures/Doses/Plans

(DICOM,

XX.X

2820 GB)

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Clinical data (CSV, zip)


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