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Click here for a description of the TCGA-HNSC data set. |
Summary
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The The Cancer Genome Atlas (TCGA) Head-Neck Phenotype Research Group is part of the Cancer Imaging ProgramProject TCGA Radiology Initiative; an effort to build a research community focused on analyzing images from the TCGA-Head and Neck Squamous Cell Carcinoma (HNSC) collection. Multiple modalities of images which correlate to the head-neck tissue data in the TCGA Data Portal are being gathered for submission to The Cancer Imaging Archive (TCIA). |
According to the TCGA page on HNSC, researchers hope to make the following types of discoveries:
- Determine whether patterns of genomic changes are different between tumors that metastasize to other regions of the body and tumors that remain in the region of origin.
- Identify genomic differences that distinguish tumors across age and smoking history.
- Identify genomic differences that are associated with viral infection.
Research and Publications
Per TCGA and TCIA Guidelines, formal permission requests are still required to submit publications using TCGA-HNSC data. Please see the following links for more information about the freedom-to-publish criteria for these data sets:
Data Source | Status |
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No restrictions; all data available without limitations. | |
Publication limitations in place until 7/07/2015;; Please check with cancerimagingarchive@mail.nih.gov prior to any publication. |
Please contact us at cancerimagingarchive@mail.nih.gov if you have any questions about these policies.
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connecting cancer phenotypes to genotypes by providing clinical images matched to tissue specimens analyzed for The Cancer Genome Atlas (TCGA). |
Imaging Source Site (ISS) Groups will be populated are being formed and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, ISS groups are given the opportunity to publish a marker paper for a given cancer type per the type per the guidelines in the table above. This opportunity will generate increased participation in building these multi-institutional data sets as they become an open community resource. Current Current The Cancer Genome Atlas Head-Neck Squamous Cell Carcinoma Collection (TCGA-HNSC source ) source sites include:
- University of Pittsburgh (UPMC) (TSS code "-CN-")
- University of North Carolina
- Vanderbilt
- MD Anderson
- Johns Hopkins University
This group has not yet been established. We will provide a point of contact for the group from the ISS site(s) as soon as possible to address scientific questions or requests to collaborate with their group.
References
The following links contain publications from the main TCGA project as well as their posted publication guidelines:
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- Carolina (TSS code "-BA-")
- Vanderbilt (TSS code "-CR-")
- MD Anderson (TSS code "-CV-")
- Johns Hopkins University (TSS code "-BB-")
Please contact us at help@cancerimagingarchive.net if you have scientific questions or are interested in collaborating with their group.
Publications
TCGA Head-Neck Phenotype Research Group Publications
- Manuscripts written by the group will be listed here as they are published.
Publications written by other members of the research community can be found on our TCIA Publications page. Please contact us at help@cancerimagingarchive.net if you have a publication you would like us to add.
TCGA Genomics Publications
Read the paper about the TCGA-HNSC genomic study in the journal Proceedings of the National Academy of Sciences. Additional TCGA publications can be found at: http://cancergenome.nih.gov/publications.
Publication Policies
Per TCGA and TCIA Guidelines, formal permission requests are no longer required to submit publications using TCGA-HNSC data. Please see the following links for more information about the freedom-to-publish criteria for these data sets:
Data Source | Status |
---|---|
No restrictions; all data available without limitations. | |
No restrictions; all data available without limitations. |
Please contact us at help@cancerimagingarchive.net if you have any questions about these policies.