The Cancer Imaging Archive (TCIA) Public Access

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Summary

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This collection contains data from the Eastern Cooperative Oncology Group (ECOG) Clinical Trial NCT02933489, “Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts". Principle Investigator: Christopher Comstock.  It was sponsored by NCI and performed by the Eastern Cooperative Oncology Group under study number EA1141. This randomized phase II trial enrolled 1,516 subjects to study how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts. Imaging and clinical data from 500 of those subjects are being made available through this collection.

Trial Outcomes

Results of the trial have been reported in the following publication:

  • Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK. Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. JAMA. 2020 Feb 25;323(8):746-756. doi: 10.1001/jama.2020.0572. Erratum in: JAMA. 2020 Mar 24;323(12):1194. 

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