Child pages
  • The Clinical Proteomic Tumor Analysis Consortium Cutaneous Melanoma Collection (CPTAC-CM)

Versions Compared

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

Summary


Excerpt

This collection contains subjects from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium Cutaneous Melanoma (CPTAC-CM) cohort. CPTAC is a national effort to accelerate the understanding of the molecular basis of cancer through the application of large-scale proteome and genome analysis, or proteogenomics. Radiology and pathology images from CPTAC patients are being collected and made publicly available by The Cancer Imaging Archive to enable researchers to investigate cancer phenotypes which may correlate to corresponding proteomic, genomic and clinical data.                              

Imaging from each cancer type will be contained in its own TCIA Collection, with the collection name "CPTAC-cancertype", and is being made available on a release schedule that is coordinated with the CPTAC program releases of proteomic and genomic data.  A summary of CPTAC imaging efforts can be found on the CPTAC Imaging Proteomics page. 

Radiology imaging is collected from standard of care imaging performed on patients immediately before the pathological diagnosis, and from follow-up scans where available.  For this reason the radiology image data sets are heterogeneous in terms of scanner modalities, manufacturers and acquisition protocols. Pathology imaging is collected as part of the CPTAC qualification workflow.  

CPTAC Imaging Special Interest Group

You can join the CPTAC Imaging Special Interest Group to be notified of webinars & data releases, collaborate on common data wrangling tasks and seek out partners to explore research hypotheses!  Artifacts from previous webinars such as slide decks and video recordings can be found on the CPTAC SIG Webinars page.

Acknowledgements

We would like to acknowledge the individuals and institutions that have provided data for this collection:

  • St. Joseph's Hospital and Medical Center, Phoenix, AZ - Special thanks to Jennifer Eschbacher, MD from the Department of Neuropathology, Catherine Seiler, PhDRosy Singh and Beth Hermes from the Biobank Core Facility, and Victor Sisneros, RT(R)(CT), CPSA.
  • BioPartners, CA - Special thanks to Alexander Gasparian, PhD.  from the Department of Drug Discovery and Biomedical Sciences, University of South Carolina College of Pharmacy, Kakhaber Zaalishvili, MD  Medical Advisor and Staff Pathologist at BioPartners, LLC, Milla Gorodnia,  President of BioPartners, Inc., Victoria Christensen, Global Business Development/Project Coordination Manager, Oksana Havryliuk, MD. Chief of Research department of radiodiagnostics of NCI (Ukraine), Marianna Gredil’, Director of BioPartners, LLC, and  Anna Legenka Chief of the Data Department at BioPartners, LLC 
  • International Institute for Molecular Oncology, Poznań, Poland - Special thanks to Maciej Wiznerowicz MD, PhD and Jan Lubiński MD PhDTomasz Czernicki MD, PhD and Andrzej Marchel MD, PhD from Central Clinical Hospital in Warsaw, Pawel Jarmużek MD, PhDJakub Stawicki MD and Piotr Makarewicz MD from Karol Marcinkowski Regional Clinical Hospital in Zielona Góra; and Wojciech Szopa MD, PhD and Wojciech Kaspera MD, PhD from Regional Clinical Hospital Sosnowiec in Poland


Added radiology imaging for 4 participants.

Version 7: Updated 2020/03/31

Localtab Group



Localtab
activetrue
titleData Access

Data Access


Data TypeDownload all or Query/FilterLicense
Radiological Images (DICOM, 14 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/TCIA-CPTAC-CM_v10_20230224.tcia?api=v2



Tcia button generator
labelSearch
urlhttps://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=CPTAC-CM




(Download requires the NBIA Data Retriever)

Tcia cc by 3

Tissue Slide Images (SVS, 107 GB)


Tcia button generator
urlhttps://faspex.cancerimagingarchive.net/aspera/faspex/external_deliveries/21?passcode=26b1b8180593cc26c6716e8f266e4125bd420cd2



Tcia button generator
labelSearch
urlhttps://pathdb.cancerimagingarchive.net/eaglescope/dist/?configurl=/system/files/collectionmetadata/202208/cptac_metadata_page_0.json&filterState=[{"id":"Tumor","title":"Tumor","field":"Tumor","operation":"eq","values":"CM"}]





(Download and apply the IBM-Aspera-Connect plugin to your browser to retrieve this faspex package) 

Tcia cc by 3

Click the Versions tab for more info about data releases.

Nci_crdc additional resources




Localtab
titleDetailed Description

Detailed Description



Radiology Image Statistics

Pathology Image Statistics

Modalities

CT, MR, PT

Pathology

Number of Participants

13

92

Number of Studies

19

N/A

Number of Series

186

N/A

Number of Images

32,091

404
Images Size (GB)

14.9

107


A Note about TCIA and CPTAC Participant Identifiers and Dates

Participant Identifiers: 

A participant with radiology and pathology images stored in TCIA is identified with a de-identified project Patient ID that is identical to the Patient ID of the same participant with clinical, proteomic, and/or genomic data stored in other CPTAC databases and web sites.

Dates: 

The radiology imaging data is in DICOM format. To provide temporal context information aligned with events in the clinical data set for each participant, TCIA has inserted information in DICOM tag (0012,0050) Clinical Trial Time Point ID. This DICOM tag contains the number of days from the date the patient was initially diagnosed pathologically with the disease to the date of the scan. E.g. a scan acquired 3 days before the diagnosis would contain the value -3. A follow up scan acquired 90 days after diagnosis would contain the value 90.

The DICOM date tags (i.e. birth dates, imaging study dates, etc.) are modified per TCIA's standard process which offsets them by a random number of days. The offset is a number of days between 3 and 10 years prior to the real date that is consistent for each TCIA image-submitting site and collection, but that varies among sites and among collections from the same site. Thus, the number of days between a participant’s longitudinal imaging studies are accurately preserved when more than one study has been archived while still meeting HIPAA requirements.




Localtab
titleCitations & Data Usage Policy

Citations & Data Usage Policy 

Tcia limited license policy


Info
titleData Citation

National Cancer Institute Clinical Proteomic Tumor Analysis Consortium (CPTAC). (2018). The Clinical Proteomic Tumor Analysis Consortium Cutaneous Melanoma Collection (CPTAC-CM) (Version 10) [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2018.ODU24GZE


Info
titleAcknowledgement

The CPTAC program requests that publications using data from this program include the following statement: “Data used in this publication were generated by the National Cancer Institute Clinical Proteomic Tumor Analysis Consortium (CPTAC).”


Info
titleTCIA Citation

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. DOI: 10.1007/s10278-013-9622-7


Other Publications Using This Data

TCIA maintains a list of publications which leverage TCIA data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.




  

(Requires NBIA Data Retriever .)

 

Localtab
titleVersions

Version 10 (Current) 2023/02/24

Data TypeDownload all or Query/Filter
Images (DICOM, 14 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/TCIA-CPTAC-CM_v10_20230224.tcia?api=v2



Tcia button generator
labelSearch
urlhttps://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=CPTAC-CM



(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GB)


Tcia button generator
urlhttps://faspex.cancerimagingarchive.net/aspera/faspex/external_deliveries/21?passcode=26b1b8180593cc26c6716e8f266e4125bd420cd2



 

Tcia button generator
labelSearch
urlhttps://cancerimagingarchive.net/datascope/cptac/home/?filter={%22Tumor%22:%5B%22CM%22%5D,%22Image_Available%22:%5B%22Yes%22%5D}



Clinical Data API (JSON -  more info


Tcia button generator
urlhttps://clinicalapi-cptac.esacinc.com/api/tcia/clinical_data/tumor_code/CM



Proteomics (web)


Tcia button generator
exttrue
labelSearch
urlhttps://proteomicsproteomic.datacommons.cancer.gov/data-portalpdc/browse/filters/program_name:Clinical%20Proteomic%20Tumor%20Analysis%20Consortium



Genomics (web)


Tcia button generator
exttrue
labelSearch
urlhttps://proteomicsportal.gdc.cancer.gov/data-portalexploration?filters=%7B%22op%22%3A%22and%22%2C%22content%22%3A%5B%7B%22op%22%3A%22in%22%2C%22content%22%3A%7B%22field%22%3A%22cases.project.program.name%22%2C%22value%22%3A%5B%22CPTAC-CM%22%5D%7D%7D%5D%7D



Radiology modality data cleanup to remove extraneous scans.

Version 9: 2020/09/03

Data TypeDownload all or Query/Filter
Images (DICOM, 14 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_v8_20200630.tcia?version=1&modificationDate=1593026979556&api=v2



Tcia button generator
labelSearch
urlhttps://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=CPTAC-CM



(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GB)


Tcia button generator
urlhttps://faspex.cancerimagingarchive.net/aspera/faspex/external_deliveries/21?passcode=26b1b8180593cc26c6716e8f266e4125bd420cd2



 

Tcia button generator
labelSearch
urlhttps://cancerimagingarchive.net/datascope/cptac/home/?filter={%22Tumor%22:%5B%22CM%22%5D,%22Image_Available%22:%5B%22Yes%22%5D}



Clinical Data API (JSON -  more info


Tcia button generator
urlhttps://clinicalapi-cptac.esacinc.com/api/tcia/clinical_data/tumor_code/CM



Changed to new Aspera download link for histopathology slides.

Version 8: Updated 2020/06/30

Genomics (web)
Data TypeDownload all or Query/Filter
Images (DICOM, 14 GBProteomics (web)
Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portal


Search
Tcia button generator
label
urlhttps://proteomicswiki.cancer.gov/data-portal

Changed to new Aspera download link for histopathology slides.

Version 8: Updated 2020/06/30

Data TypeDownload all or Query/Filter
Images (DICOM, 14 GB)
Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_v8_20200630.tcia?version=1&modificationDate=1593026979556&api=v2
Tcia button generator
labelSearch
urlhttps://www.cancerimagingarchive.net/nbia-search/?CollectionCriteria=CPTAC-CM
Tissue Slide Images (SVS, 107 GB)
Tcia button generator
urlhttps://pathology.cancerimagingarchive.net/download/CM/
Tcia button generator
labelSearch
urlhttps://cancerimagingarchive.net/datascope/cptac/home/?filter={%22Tumor%22:%5B%22CM%22%5D,%22Image_Available%22:%5B%22Yes%22%5D}
Clinical Data API (JSON -  more info
cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_v8_20200630.tcia?version=1&modificationDate=1593026979556&api=v2


  

Tcia button generator
urlhttps://clinicalapi-cptac.esacinc.com/api/tcia/clinical_data/tumor_code/CM
Proteomics (web)
Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portal
Genomics (web)
Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portal

(Requires NBIA Data Retriever .)

 

Proteomics (web)


Data TypeDownload all or Query/Filter
Images (DICOM, 10.7 GB)
Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_v7_20200331.tcia?version=1&modificationDate=1585662962935&api=v2
Tissue Slide Images (SVS, 107 GB)
Tcia button generator
urlhttps://pathology.cancerimagingarchive.net/download/CM/
Clinical Data API (JSON -  more info
Tcia button generator
urlhttps://clinicalapi-cptac.esacinc.com/api/tcia/clinical_data/tumor_code/CM
Tcia button generator
labelSearch
urlhttps://proteomicswww.cancer.gov/data-portalcancerimagingarchive.net/nbia-search/?CollectionCriteria=CPTAC-CM




(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GBGenomics (web)


label
Tcia button generator
Searchurlhttps://proteomicspathology.cancercancerimagingarchive.gov/data-portal

Added 3 Radiology subjects & 2 Pathology subjects.

Version 6: Updated 2019/12/13

net/download/CM/



 

Data TypeDownload all or Query/FilterImages (DICOM, 7.3 GB)

Tcia button generator
labelSearch
urlhttps://
wiki.
cancerimagingarchive.net/
download
datascope/
attachments
cptac/
33948224/CPTAC-CM_batch4_Dec2019.tcia?version=1&modificationDate=1576275055232&api=v2

(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GB)
home/?filter={%22Tumor%22:%5B%22CM%22%5D,%22Image_Available%22:%5B%22Yes%22%5D}



Clinical Data API (JSON -  more info


Tcia button generator
urlhttps://
pathology
clinicalapi-cptac.
cancerimagingarchive.net/download/CM/Clinical Data (CSV)(Coming Soon)
esacinc.com/api/tcia/clinical_data/tumor_code/CM



Added radiology imaging for 4 participants.

Version 7: Updated 2020/03/31


Data TypeDownload all or Query/Filter
Images (DICOM, 10.7 GB
Proteomics (web
)


Tcia button generator
labelSearch
urlhttps://
proteomics
wiki.
cancer.gov/data-portal
cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_v7_20200331.tcia?version=1&modificationDate=1585662962935&api=v2



(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GB
Genomics (web
)


Tcia button generator
labelSearch
urlhttps://
proteomics
pathology.
cancer
cancerimagingarchive.
gov/data-portal

Added 3 new Radiology Subjects.

Version 5: Updated 2019/10/30

net/download/CM/



 

Clinical Data API (JSON -  more info
Data TypeDownload all or Query/FilterImages (DICOM, 4.1 GB)


Tcia button generator
urlhttps://
wiki
clinicalapi-cptac.
cancerimagingarchive
esacinc.
net
com/api/
download
tcia/clinical_data/tumor_code/CM




Added 3 Radiology subjects & 2 Pathology subjects.

Version 6: Updated 2019/12/13


Data TypeDownload all or Query/Filter
Images (DICOM, 7.3
attachments/33948224/CPTAC-CM_batch3_Mar2019.tcia?version=1&modificationDate=1554002679650&api=v2

(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107
GB)


Tcia button generator
urlhttps://
pathology
wiki.cancerimagingarchive.net/download/attachments/33948224/
CM/Proteomics (web) Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portal
CPTAC-CM_batch4_Dec2019.tcia?version=1&modificationDate=1576275055232&api=v2



(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GB
Genomics (web
)


Tcia button generator
labelSearch
urlhttps://
proteomics
pathology.
cancer.gov/data-portal

Added Pathology Subjects

Version 4
cancerimagingarchive.net/download/CM/




Added 3 new Radiology Subjects.

Version 5: Updated 2019/

06

10/30


Data TypeDownload all or Query/Filter
Images (DICOM, 4.1 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_batch3_Mar2019.tcia?version=1&modificationDate=1554002679650&
api=v2

(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 99 GB) Tcia button generator
urlhttps://pathology.cancerimagingarchive.net/download/CM/
Proteomics (web) Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portal
Genomics (web
api=v2



(Requires NBIA Data Retriever .)

Tissue Slide Images (SVS, 107 GB)


Tcia button generator
labelSearch
urlhttps://
proteomics
pathology.
cancer.gov/data-portal

Corrected ClinicalTrialTimepointID in 1 subject.

Version 3
cancerimagingarchive.net/download/CM/




Added Pathology Subjects

Version 4: Updated 2019/

03

06/

31

30


Data TypeDownload all or Query/Filter
Images (DICOM, 4.1 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_batch3_Mar2019.tcia?version=1&modificationDate=1554002679650&api=v2



(Requires NBIA Data Retriever .)

Tissue Slide Images (
web
SVS, 99 GB)


Tcia button generator
labelSearch
urlhttps://pathology.cancerimagingarchive.net/download/CM/




Corrected ClinicalTrialTimepointID in 1 subject.

Version 3 : Updated 2019/03/31


/datascope/cptac/
Data TypeDownload all or Query/Filter
Images (DICOM, 4.1 GBProteomics (web)


Search
Tcia button generator
label
urlhttps://proteomicswiki.cancer.gov/data-portalcancerimagingarchive.net/download/attachments/33948224/CPTAC-CM_batch3_Mar2019.tcia?version=1&modificationDate=1554002679650&api=v2



(Requires NBIA Data Retriever .)

Tissue Slide Images Genomics (web)


Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portalcancerimagingarchive.net/datascope/cptac/




Added subjects

Version 2 : Updated 2018/06/30


Genomics Images (web)
Data TypeDownload all or Query/Filter
Images (DICOM, 3.3 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/TCIA_CPTAC-CM-2018-06-30-doiJNLP-MbkGSemg.tcia?version=1&modificationDate=1534787045566&api=v2


  

(Requires NBIA Data Retriever.)

Tissue Slide Images (web)
Tcia button generator
labelSearch
urlhttps://cancerimagingarchive.net/datascope/cptac/
Proteomics (web)
Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portal


Tcia button generator
labelSearch
urlhttps://proteomics.cancer.gov/data-portalcancerimagingarchive.net/datascope/cptac/




Version 1: Updated 2018/01/10


Data TypeDownload all or Query/Filter
Images (DICOM, 1.59 GB)


Tcia button generator
urlhttps://wiki.cancerimagingarchive.net/download/attachments/33948224/CPTAC-CM-B1-doiJNLP-RPBJyzzR.tcia?version=1&modificationDate=1534787046032&api=v2


  

Tissue Slide Images (web)


Tcia button generator
labelSearch
urlhttps://cancerimagingarchive.net/datascope/cptac/



Proteomics (web)


Tcia button generator
exttrue
labelSearch
urlhttps://proteomicsproteomic.datacommons.cancer.gov/data-portal/pdc/browse/filters/program_name:Clinical%20Proteomic%20Tumor%20Analysis%20Consortium



Genomics (web)


Tcia button generator
exttrue
labelSearch
urlhttps://proteomicsproteomic.datacommons.cancer.gov/data-portal/pdc/browse/filters/program_name:Clinical%20Proteomic%20Tumor%20Analysis%20Consortium