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The Reference Image Database to Evaluate Therapy Response (RIDER) database is a targeted data collection for the purpose of generating used to generate an initial consensus on how to harmonize data collection and analysis for quantitative imaging methods as applied to measure the response to drug or radiation therapy. |
The long term goal is to provide a resource to permit harmonized methods for data collection and analysis across different commercial imaging platforms , as required to support multi-site clinical trials, using imaging as a biomarker for therapy response. Thus, the database should permit an objective comparison of methods for data collection and analysis as a national and international resource as described in the first RIDER white paper report (2006):
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All the image data are DICOM compliant. The data collection has two phases as described below, which have resulted in several distinct image Collections.
RIDER Contracts (2007-Beyond)
The National Cancer Institute (NCI) has exercised a series of contracts with specific academic sites for collection of repeat "coffee break," and longitudinal phantom, and patient data for a range of imaging modalities (currently CT, PET CT, DCE MRI, DW computed tomography CT positron emission tomography (PET) CT, dynamic contrast-enhanced magnetic resonance imaging [DCE MRI]), diffusion-weighted [DW] MRI) and organ sites (currently lung, breast, and neuro). The goals are as follows:
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