Summary
The Cancer Genome Atlas (TCGA) Lung Phenotype Research Group is part of the Cancer Imaging Program TCGA Radiology Initiativefocused on analyzing images from the TCGA- Lung Adenocarcinoma (LUAD) collection. Multiple modalities of images which correlate to the lung tissue data in TCGA’s Data Portal are being gathered for submission to The Cancer Imaging Archive (TCIA).According to the TCGA page on lung adenocarcinoma, researchers hope to make the following types of discoveries about lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC):
- Pinpoint gene changes that divide squamous and adenocarcinoma tumors into molecular subgroups
- Distinguish patterns of gene changes between adenocarcinoma and squamous cell carcinoma
- Distinguish genomic changes between smokers and non-smokers
Research and Publications
Per TCGA and TCIA Guidelines formal permission requests are still required to submit publications using TCGA-LUAD data. Please see the following links for more information about the freedom-to-publish criteria for these data sets:
Data Source | Status |
---|---|
No restrictions; all data available without limitations | |
Projects have not reached 100 imaging cases; Please check with cancerimagingarchive@mail.nih.gov prior to any publication |
Please contact us at cancerimagingarchive@mail.nih.gov if you have any questions about these policies.
TCGA Lung Marker Paper and Image Source Sites (ISS)
Imaging Source Site (ISS) Groups will be populated and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this will generate increased participation in the building of these multi-institutional data sets that become an open community resource. Current TCGA-LUAD source sites include:
- Washington University in St. Louis
- UPMC
This group has not yet been established. We will provide a point of contact for the group from the ISS site(s) as soon as possible to address scientific questions or requests to collaborate with their group.
References
The following links contain publications from the main TCGA project, as well as their posted publication guidelines.
TCGA 2nd Annual Symposium